Neonatal outcome with 0ral versus Vaginal Misoprostol for Labour Induction

Authors

  • Nadira Sultana Assistant Professor, Dept. of Gynae and obs, Basundhara Ad-din Medical College and Hospital, Dhaka
  • Dipa Saha Assistant Professor, Dept. of Pediatrics, Basundhara Ad-din Medical College & Hospital, Dhaka
  • Marium Begum Associate Professor, Dept. of Pediatrics, Basundhara Ad-din Medical College & Hospital, Dhaka
  • Sabiha Yeasmin Assistant Surgeon, Burichung Upazilla Health Complex, Comilla
  • Khairul Alam Assistant Registrar, Dept. of Pediatrics, Sarkari Karmachari Hospital, Dhaka
  • Arifa Akhter Assistant Professor, Dept. of Gynae and obs, Basundhara Ad-din Medical College & Hospital, Dhaka
  • Wahida Hasin Assistant Professor, Dept. of Community Medicine, Basundhara Ad-din Medical College & Hospital, Dhaka

DOI:

https://doi.org/10.3329/nimcj.v8i2.32556

Keywords:

Misoprostol, Induction of labour, neonatal outcome

Abstract

Background : Misoprostol is being used widely through different routes for induction of labour. Neonatal outcome may be different with using different routes.

Objective : To see the neonatal outcome for induction of labour by misoprostol in oral versus vaginal route.

Materials and Methods : This prospective and comparative study was carried out in the dept. of Obstetrics and Gynecology of Jalalabad Ragib- Rabeya Medical College and Hospital, Sylhetfrom July 2008 to June 2009.A total 200 pregnant women completed 28 weeks pregnancy upto 42 weeks were selected for the study.Out of which 100 pregnant women were includedin oral misoprostol group and 100 in vaginal misoprostol groupby simple randomization. Inclusion criteria were single live fetus with cephalic presentation, normal fetal heart rate, adequate pelvis and Bishop score <5. Exclusion criteria were previous uterine scar, estimated fetal weight >4 kg, parity more than 3 and history of hypersensitivity to misoprostol. Neonatal outcome in terms of Apgar Score, passage of meconium, perinatal depression and admission to Neonatal Intensive Care Unit (NICU) compared between two groups.

Results : Most of the neonate in vaginal group had low Apgar score. Two percent neonate had Apgar score 2 and 86% had 4-6 in 1 minute in vaginal group whereas in oral group it was 4-6 in 88%.Perinatal depression more in vaginal group 18(18%) than oral group 8(8%). More neonate need admission to Neonatal Intensive Care Unit (NICU) in vaginal group 4(4%) than oral group 2(2%). Only 1% neonate passed meconium in vaginal group.

Conclusion : This study concluded that neonatal outcome was better and safe with oral misoprostol than vaginal route.

Northern International Medical College Journal Vol.8(2) January 2017: 228-230

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Author Biography

Nadira Sultana, Assistant Professor, Dept. of Gynae and obs, Basundhara Ad-din Medical College and Hospital, Dhaka



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Published

2017-05-14

How to Cite

Sultana, N., Saha, D., Begum, M., Yeasmin, S., Alam, K., Akhter, A., & Hasin, W. (2017). Neonatal outcome with 0ral versus Vaginal Misoprostol for Labour Induction. Northern International Medical College Journal, 8(2), 228–230. https://doi.org/10.3329/nimcj.v8i2.32556

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Original Articles