Cucumis Sativus L. Foamy Extract Induces Apoptosis In Mda-Mb-231 Cells
Cucumber Extract Induces Apoptosis in Cancer Cells
DOI:
https://doi.org/10.3329/sja.v22i2.74341Keywords:
Apoptosis, Cucumis sativus L, Foamy extract, HR-LCMS,MDA-MB-231cells.Abstract
Cucumis sativus L. (C. sativus) is considered as an important salad fruit as well as vegetable, fruits. It is consumed as herbal medicines. Here, we investigated the effects of foamy extract on the viability of the MDA-MB-231 human cells. Results revealed that extract significantly (P < 0:05) inhibited the proliferation of cells in comparatively lower toxic effects. The IC50 was found to be 116.11 µg/mL against MDA-MB-231 cells, Annexin V/PI staining assays indicated that it stimulated apoptosis in MDA-MB-231. Treated cells were observed to show greater incidence of apoptotic cells, when compared to the untreated cells. Thus, it is efficient enough to induce apoptosis, in MDA-MB-231 cells. Cucumber foamy extract may prove to be an important source of natural anticancer agents.
SAARC J. Agric., 22(2): 55-66 (2024)
Downloads
88
66
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 SAARC Agriculture Centre
This work is licensed under a Creative Commons Attribution 4.0 International License.
© SAARC Agricultural Centre
Copyright on any research article is transferred in full to SAARC Journal of Agriculture upon publication in the journal. The copyright transfer includes the right to reproduce and distribute the article in any form of reproduction (printing, electronic media or any other form).
Articles in the SAARC Journal of Agriculture are Open Access articles published under a Creative Commons Attribution 4.0 International License] CC BY License.
This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
