Effect of Fenugreek (Methi) on the Thymic volume in Streptozotocin-induced Diabetic Rats

Abstract

Effect of fenugreek (Trigonella foenumgraecum) on thymic volume was studied in 30 long Evans
rats. Among the total, 10 were treated with only vehicle (non-diabetic control - group A); 10 were
treated with streptozotocin only (diabetic control - group B) and 10 were treated with fenugreek
(fenugreek treated - group C). Mean relative thymic volumes were 0.22210.018 ml/100 gm of
corresponding final body weight (Mean 1 SEM), 0.14710.015 and 0.19910.020 in group A, B and C
respectively. In non-diabetic control group the thymic volume was significantly higher (p=0.005)
than that of diabetic control group. In fenugreek treated diabetic group the volume was also
significantly higher (p=0.05) from that of diabetic control group and very much nearer to nondiabetic
control group (p=0.398). Fenugreek may preserve the thymic volume considerably in
diabetic rats.

doi: 10.3329/taj.v16i1.3892

TAJ June 2003; Vol.16(1): 1-4