Antibody Response of Covishield Vaccine among Health Care Workers at Rajshahi Medical College Hospital- A Cross-Sectional Study

Authors

  • Md Azizul Haque Associate Professor, Department of Medicine, Rajshahi Medical College, Bangladesh
  • Mohammad Hasan Tarik Professor, Department of Medicine, Rajshahi Medical College, Bangladesh
  • Md Ruhul Amin Junior Consultant (Medicine), Upazilla Health Complex, Tanore, Rajshahi, Bangladesh
  • Md Jahedul Islam Registrar, Department of Medicine, Rajshahi Medical College Hospital, Bangladesh
  • Md Ariful Hasan Registrar, Department of Medicine, Rajshahi Medical College Hospital, Bangladesh
  • Md Fazlul Kabir Bhuiyan Department of Neuromedicine, Rajshahi Medical College Hospital, Bangladesh

DOI:

https://doi.org/10.3329/taj.v34i2.58549

Keywords:

Antibody response, Covishield, SARS CoV-2

Abstract

Background: Nationwide vaccination against SARS CoV-2 is the hope for stopping the pandemic and death from COVID-19. Till today several vaccines have been developed. In Bangladesh, the Covishield vaccine was the first coronavirus vaccine that was administered to health care workers on a priority basis. To assess antibody response in our community, evaluation of response in this group was necessary.

Objectives: Our main aim of this study was to evaluate antibody response to SARS CoV-2 after vaccination with the Covishield vaccine in health care workers.

Patients and Methods: It was a cross-sectional type study. Eighty-seven purposively collected health care workers were included in the study. Demographic profile, Co-morbidities, and other variables were recorded in a questionnaire. Blood samples were collected to assess SARS CoV-2 specific antibody.

Results: Mean age in our study was 41.29±7.87 years. Most of them were between 35 to 44 years of age. Male: Female ratio was 3.35:1. Obesity (BMI>25) was present in 25.9% of individuals, hypertension in 33.3%, and DM in 14.9% of individuals. Overall 82.8% were vaccinated with the Covishield vaccine, and the remaining were not vaccinated. 96.6% were found to be antibody positive. All individuals (100%) who were either had a history of COVID-19 or received at least one shot of the Covishield vaccine were found antibody positive.

Conclusion: Covishield vaccine was found to be highly effective in producing antibody response among healthcare workers.

TAJ 2021; 34: No-2: 01-08

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Published

2022-03-08

How to Cite

Haque, M. A. ., Tarik, M. H. ., Amin, M. R. ., Islam, M. J. ., Hasan, M. A. ., & Bhuiyan, M. F. K. . (2022). Antibody Response of Covishield Vaccine among Health Care Workers at Rajshahi Medical College Hospital- A Cross-Sectional Study. TAJ: Journal of Teachers Association, 34(2), 1–8. https://doi.org/10.3329/taj.v34i2.58549

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Original Articles