Correlation between Insulin Resistance and LVEF in non Diabetic Chronic Heart Failure Patients admitted in a Tertiary Care Hospital

Authors

  • Md Azharul Islam Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Manzoor Mahmood Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Khurshed Ahmed Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Sajal Krishna Banerjee Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Syed Ali Ahsan Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Chaudhury Meshkat Ahmed Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • AKM Imtiaz Akand Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Sujoy Kumar Saha Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Fysal Faruq Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Kamruzzman Siddiki Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • AKM Fazlur Rahman Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Md Fakhrul Islam Khaled Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • SM Mustafa Zaman Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Farida Yeasmin Department of Nuclear Medicine, National Institute of Nuclear Medicine and Allied Science, Shahbagh, Dhaka
  • Parveen Akter Kurmitola General Hospital, Dhaka
  • Md Harisul Hoque Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka

DOI:

https://doi.org/10.3329/uhj.v17i2.54365

Keywords:

Insulin Resistance, LVEF

Abstract

Background: Insulin resistance is a well-established composite index of systemic inflammatory and metabolic disorders. A wide variety of methods like, HOMA-IR (Homeostatic model assessment insulin resistance), FGIR (Fasting glucose insulin ratio), ISI-Composite (an index of whole body insulin sensitivity), QUICKI (quantitative insulin sensitivity check index) etc are available for assessing IR. Objective: To find out the correlation between insulin resistance and LVEF in non diabetic chronic heart failure patients. Methodology: This cross sectional study was carried out in the Department of Cardiology in Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka from February, 2019 to June, 2020. Patients admitted with chronic heart failure with reduced ejection fraction were included in this study. Patients with diabetic, prediabetic and patient who did not give written informed consent were excluded in this study. Results: LVEF 25-29% was 16 patients out of which 10(66.7%) had significant insulin resistance. LVEF 30- 34% was found in 28 patients, among them 16(41.0%) had no insulin resistance. LVEF 35-39% was found in 19 patients out of which 18(46.2%) had no insulin resistance. The difference was statistically significant (p<0.05). A negative correlation (r=-0.340; p=0.006) was found between insulin resistance and LVEF. Conclusion: Majority non diabetic chronic heart failure patients had no insulin resistance. Significant negative correlation was found between insulin resistance and LVEF.

University Heart Journal Vol. 17, No. 2, Jul 2021; 99-102

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Published

2021-06-28

How to Cite

Islam, M. A., Mahmood, M., Ahmed, K., Banerjee, S. K., Ahsan, S. A., Ahmed, C. M., Akand, A. I., Saha, S. K., Faruq, F., Siddiki, K., Rahman, A. F., Khaled, M. F. I., Zaman, S. M., Yeasmin, F., Akter, P., & Hoque, M. H. (2021). Correlation between Insulin Resistance and LVEF in non Diabetic Chronic Heart Failure Patients admitted in a Tertiary Care Hospital. University Heart Journal, 17(2), 99–102. https://doi.org/10.3329/uhj.v17i2.54365

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Original Articles