Biological activity studies of Sensevieria hyacinthoides extracts

Authors

  • Mohammad Emdadul Islam Department of Chemistry, Habibullah Bahar College, Dhaka, Bangladesh
  • Tofail Ahmed Chowdhury Department of Chemistry, University of Dhaka, Bangladesh
  • Nasim Sultana Analytical Research Division, BCSIR Laboratories, Dr. Qudrat-i-Khuda Road, Dhaka, Bangladesh
  • Abul Hasnat Muhammad Solaiman Department of Horticulture, Sher-e-Bangla Agricultural University, Dhaka-1207, Bangladesh
  • SM Anamul Arefin Fab Lab SAU, Sher-e-Bangla Agricultural University, Dhaka-1207, Bangladesh

DOI:

https://doi.org/10.3329/aajbb.v5i1.53857

Keywords:

antibacterial screening; bioassay; cytotoxicity; free radical scavengers; Sensevieria hyacinthoides

Abstract

Biological activity was studied of the different solvent extracts such as n-hexane, ethyl acetate, n-butanol, and methanol extracts of the rhizomes of Sensevieria hyacinthoides. The cytotoxic potential were examined by using brine shrimp lethality bioassay. Ethyl acetate extract exhibited quite potent activity in brine shrimp lethality bioassay with LC50 1.95 μg/mL, respectively. These result suggested that it might contain antitumor or cytotoxic agent. The ethyl acetate extract showed significant free radical scavenging activity with IC50 10.51 μg/mL and demonstrated excellent antibacterial activity. The free radical scavenging activity of the solvent extracts (n-hexane, ethyl acetate and n-butanol) were assayed by using DPPH method. The IC50 for Vit-c (Ascorbic acid) and ethyl acetate extract were found to be 3.91 and 10.51 μg/mL, respectively.

Asian Australas. J. Biosci. Biotechnol. 2020, 5 (1), 15-20

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Published

2020-04-30

How to Cite

Islam, M. E., Chowdhury, T. A., Sultana, N., Muhammad Solaiman, A. H., & Arefin, S. A. (2020). Biological activity studies of Sensevieria hyacinthoides extracts. Asian-Australasian Journal of Bioscience and Biotechnology, 5(1), 15–20. https://doi.org/10.3329/aajbb.v5i1.53857

Issue

Vol. 5 No. 1 (2020)

Section

Research Articles