Biofilm Formation and Its Association with Antimicrobial Resistance among Clinical Isolates of Acinetobacter baumanii at a Tertiary Care Hospital in Dhaka City of Bangladesh

Authors

  • Sharmeen Sultana Assistant Professor, Department of Microbiology, Monno Medical College, Manikganj, Bangladesh
  • SM Shamsuzzaman Professor & Head, Department of Microbiology, Dhaka Medical College, Dhaka, Bangladesh
  • Md Abdullah Yusuf Associate Professor, Department of Microbiology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • M Asifudduza Phase-B, Resident (MD-Cardiology), National Heart Foundation Hospital & Research Institute, Dhaka, Bangladesh
  • Tania Rahman Assistant Professor, Department of Microbiology, Khwaja Yunus Ali Medical College, Sirajganj, Bangladesh;
  • Momtaz Begum Assistant Professor, Department of Microbiology, Dhaka Community Medical College, Dhaka, Bangladesh
  • Tarana Jahan Assistant Professor, Department of Microbiology, Monno Medical College, Manikganj, Bangladesh

DOI:

https://doi.org/10.3329/bjid.v8i2.59634

Keywords:

Acinetobacter baumannii; biofilm; tissue culture plate method; antimicrobial resistance

Abstract

Background: Acinetobacter baumanii is responsible for nosocomial infections which are related to the biofilm forming capacity of this pathogen.

Objective: The purpose of the present study was to detect biofilm formation in clinical isolates of Acinetobacter baumannii and to observe relationship between biofilm formations with its antimicrobial resistance.

Methodology: This cross-sectional study was conducted in the Department of Microbiology of Dhaka Medical College and Hospital, Dhaka, Bangladesh from July 2015 to June 2016. Acinetobacter baumannii was isolated from different specimens and was identified and were screened for biofilm production by tissue culture plate method. Antimicrobial susceptibility test was done by disc diffusion method.

Results: A total 300 samples were studied of which 26(8.7%) were Acinetobacter baumannii. From 26 isolated Acinetobacter baumannii, 16(61.5%) were biofilm producers. Biofilm producing Acinetobacter baumannii were 100% resistant to ceftriaxone, ceftazidime, amoxiclav, amikacin and ciprofloxacin. Resistance to imipenem, meropenem, cephotaxime, cefepime and gentamicin were also higher among biofilm producing Acinetobacter baumannii isolates than non-biofilm producers.

Conclusions: In conclusion the ability of Acinetobacter baumannii forms biofilm and biofilm production has strong association with antimicrobial resistance.

Bangladesh Journal of Infectious Diseases December 2021;8(2):82-86

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Published

2022-05-09

How to Cite

Sultana, S. ., Shamsuzzaman, S., Yusuf, M. A. ., Asifudduza, M. ., Rahman, T. ., Begum, M. ., & Jahan, T. . (2022). Biofilm Formation and Its Association with Antimicrobial Resistance among Clinical Isolates of Acinetobacter baumanii at a Tertiary Care Hospital in Dhaka City of Bangladesh. Bangladesh Journal of Infectious Diseases, 8(2), 82–86. https://doi.org/10.3329/bjid.v8i2.59634

Issue

Vol. 8 No. 2 (2021)

Section

Original Articles

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Copyright (c) 2021 Sharmeen Sultana, SM Shamsuzzaman, Md Abdullah Yusuf, M Asifudduza, Tania Rahman, Momtaz Begum, Tarana Jahan

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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