Serum Interleukin-6 (IL-6) Level and Glycemic Control of Covid-19 Exposed Diabetic Patients in a Selected District Diabetic Hospital of Bangladesh
DOI:
https://doi.org/10.3329/bjid.v11i2.75626Keywords:
COVID-19, Interleukin-6, TNF-alpha, DM, CytokineAbstract
Background: The COVID-19 pandemic worsened diabetes management, increasing the risk of complications like DKA and HHS, requiring close blood glucose monitoring.
Objective: The objective of this study was to examine the relationship between serum IL-6 levels and glycemic control in COVID-19-exposed diabetic patients in Bangladesh.
Methodology: This cross-sectional study was conducted at Ahad Diabetic Health Complex, Jessore, from October 2022 to May 2023, involving 85 diabetic patients aged 18 and above, exposed to COVID-19. Data on socio-demographics, glycemic status, and COVID-19 exposure were collected using a semi-structured questionnaire. Blood samples were taken for serum interleukin 6 (IL-6) analysis. The study followed ethical guidelines, with approval from relevant ethical review committees, and used SPSS for statistical analysis.
Results: Among the respondent’s majority were middle and elderly age group people with mean 8.0741±11.45401years with almost equal male female ratio. By nutritional status 48.2% were of Normal weight, followed by 43.5% were Pre obese, and 4.7% were obesed. Among the respondents 52.9% cases had family history of diabetes, 41.2% caseshad COVID symptoms but only 17.6% were COVID-19 positive with having COVID symptoms. Among the respondents, 60.0% were suffering from diabetes for 1 to 5 years, 28.2% for 6 to 10 years, 7.1% for 11 to 15 years and only 4.7% were suffering for 13 – 20 years. The mean Serum IL-6 was 5.66±2.245 among the respondents having COVID-19 positive while it was more 7.10±6.137 among the rests. Mean blood glucose level was 14.7933±7.45381 mmol/L who were COVID-19 positive and 12.9876±5.69122 mmol/L among rests.
Conclusion: The study found a significant association between serum IL-6 levels and age, suggesting that age may influence inflammation in COVID-19-exposed diabetic patients.
Bangladesh Journal of Infectious Diseases, December 2024;11(2):131-137
Downloads
81
48
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Arifa Akram
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright
Copyright on any research article in the Bangladesh Journal of Infectious Diseases is retained by the author(s).
The authors grant the Bangladesh Infection Research Association a license to publish the article and identify itself as the original publisher.
Articles in the Bangladesh Journal of Infectious Diseases are Open Access articles published under the Creative Commons CC BY-NC License (https://creativecommons.org/licenses/by-nc/4.0/)
This license permits use, distribution and reproduction in any medium, provided the original work is properly cited, and it is not used for commercial purposes.
