Prevalence of Extended Spectrum b-Lactamases (ESBL) Producers Among Gram-Negative Bacilli in Wound Infection

Authors

  • Abu Hena Md Saiful Karim Chowdhury Department of Pathology, Chittagong Medical College, Chittagong
  • Md Anwar Husain Department of Microbiology, Chittagong Medical College, Chittagong
  • Nasima Akter Department of Microbiology, Chittagong Medical College, Chittagong
  • Khan Mashrequl Alam Department of Microbiology, Chittagong Medical College, Chittagong
  • Arup Kanti Dewanjee Department of Microbiology, Chittagong Medical College, Chittagong
  • Shakeel Ahmed Department of Microbiology, Chittagong Medical College, Chittagong
  • Zakir Hossain Department of Microbiology, Chittagong Medical College, Chittagong
  • Arifur Rahman Department of Microbiology, Chittagong Medical College, Chittagong
  • Towhida Naheen Department of Anatomy, University of Science & Technology Chittagong (USTC), Chittagong
  • Md Abdul Mazed Department of Microbiology, Cox?s Bazar Medical College, Cox's Bazar
  • Sanjoy Kanti Biswas Department of Microbiology, Chattagram Maa-O-Shisu Hospital Medical College Chittagong
  • Md Ehsanul Hoque Department of Microbiology, Rangamati Medical College, Rangamati

DOI:

https://doi.org/10.3329/cmoshmcj.v15i1.28758

Keywords:

Gram-negative bacilli, ESBL, Klebsiella Species, Infection

Abstract

Background: Extended Spectrum b -Lactameses Producing Organisms (ESBLs) are increasing in number and causing more severe infections because of their continuous mutation and multidrug resistance property with limited therapeutic option.

Aims and Objectives: Present study was undertaken to detect the prevalence of the ESBLs producing bacteria in wound infection, so as to provide a base line data in treating them & prevent unnecessary use of antibiotics

Methods: Isolated gram-negative bacteria initially screened by Minimum Inhibitory Concentration (MIC) ESBLs breakpoints. Then suspected ESBLs producers were confirmed by Phenotypic confirmatory test. Results: 105 (One hundred five) (91.30%) bacterial strains were isolated from 115 samples of wound swab & pus from different patients were studied of which 84(80.00%) were Gram-negative and 21(20.00%) were Gram-positive. Among the isolated Gram-negative bacteria 79(94.05%) were found suspected ESBLs producers of which 54(68.35%) were found as confirmed ESBL producers. The prevalence of ESBLs producing organisms in the present study were found to be 64.29% and Klebsiella spp as most prevalent ESBLs producers.

Conclusion: It is essential to report ESBL production along with routine sensitivity reporting, which will help the clinician in prescribing the proper antibiotics.

Chatt  Shi Hosp Med Coll J; Vol.15 (1); Jan 2016; Page 26-30

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Author Biography

Abu Hena Md Saiful Karim Chowdhury, Department of Pathology, Chittagong Medical College, Chittagong



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Published

2016-07-17

How to Cite

Karim Chowdhury, A. H. M. S., Husain, M. A., Akter, N., Alam, K. M., Dewanjee, A. K., Ahmed, S., Hossain, Z., Rahman, A., Naheen, T., Mazed, M. A., Biswas, S. K., & Hoque, M. E. (2016). Prevalence of Extended Spectrum b-Lactamases (ESBL) Producers Among Gram-Negative Bacilli in Wound Infection. Chattagram Maa-O-Shishu Hospital Medical College Journal, 15(1), 26–30. https://doi.org/10.3329/cmoshmcj.v15i1.28758

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Original Articles