Prevalence of Extended Spectrum b-Lactamases (ESBL) Producers Among Gram-Negative Bacilli in Wound Infection

Authors

  • Abu Hena Md Saiful Karim Chowdhury Department of Pathology, Chittagong Medical College, Chittagong
  • Md Anwar Husain Department of Microbiology, Chittagong Medical College, Chittagong
  • Nasima Akter Department of Microbiology, Chittagong Medical College, Chittagong
  • Khan Mashrequl Alam Department of Microbiology, Chittagong Medical College, Chittagong
  • Arup Kanti Dewanjee Department of Microbiology, Chittagong Medical College, Chittagong
  • Shakeel Ahmed Department of Microbiology, Chittagong Medical College, Chittagong
  • Zakir Hossain Department of Microbiology, Chittagong Medical College, Chittagong
  • Arifur Rahman Department of Microbiology, Chittagong Medical College, Chittagong
  • Towhida Naheen Department of Anatomy, University of Science & Technology Chittagong (USTC), Chittagong
  • Md Abdul Mazed Department of Microbiology, Cox?s Bazar Medical College, Cox's Bazar
  • Sanjoy Kanti Biswas Department of Microbiology, Chattagram Maa-O-Shisu Hospital Medical College Chittagong
  • Md Ehsanul Hoque Department of Microbiology, Rangamati Medical College, Rangamati

DOI:

https://doi.org/10.3329/cmoshmcj.v15i1.28758

Keywords:

Gram-negative bacilli, ESBL, Klebsiella Species, Infection

Abstract

Background: Extended Spectrum b -Lactameses Producing Organisms (ESBLs) are increasing in number and causing more severe infections because of their continuous mutation and multidrug resistance property with limited therapeutic option.

Aims and Objectives: Present study was undertaken to detect the prevalence of the ESBLs producing bacteria in wound infection, so as to provide a base line data in treating them & prevent unnecessary use of antibiotics

Methods: Isolated gram-negative bacteria initially screened by Minimum Inhibitory Concentration (MIC) ESBLs breakpoints. Then suspected ESBLs producers were confirmed by Phenotypic confirmatory test. Results: 105 (One hundred five) (91.30%) bacterial strains were isolated from 115 samples of wound swab & pus from different patients were studied of which 84(80.00%) were Gram-negative and 21(20.00%) were Gram-positive. Among the isolated Gram-negative bacteria 79(94.05%) were found suspected ESBLs producers of which 54(68.35%) were found as confirmed ESBL producers. The prevalence of ESBLs producing organisms in the present study were found to be 64.29% and Klebsiella spp as most prevalent ESBLs producers.

Conclusion: It is essential to report ESBL production along with routine sensitivity reporting, which will help the clinician in prescribing the proper antibiotics.

Chatt  Shi Hosp Med Coll J; Vol.15 (1); Jan 2016; Page 26-30

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Author Biography

Abu Hena Md Saiful Karim Chowdhury, Department of Pathology, Chittagong Medical College, Chittagong



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Published

2016-07-17

How to Cite

Karim Chowdhury, A. H. M. S., Husain, M. A., Akter, N., Alam, K. M., Dewanjee, A. K., Ahmed, S., … Hoque, M. E. (2016). Prevalence of Extended Spectrum b-Lactamases (ESBL) Producers Among Gram-Negative Bacilli in Wound Infection. Chattagram Maa-O-Shishu Hospital Medical College Journal, 15(1), 26–30. https://doi.org/10.3329/cmoshmcj.v15i1.28758

Issue

Vol. 15 No. 1 (2016)

Section

Original Articles

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