Genotyping of Virulence Factors of Uropathogenic Escherichia Coli from Chittagong, Bangladesh

Authors

  • Laila Khaleda Department of Genetic Engineering and Biotechnology, University of Chittagong, Chittagong-4331,Bangladesh
  • Bashudev Rudra Department of Genetic Engineering and Biotechnology, University of Chittagong, Chittagong-4331,Bangladesh
  • Inzamamul Ismail Shawon Department of Genetic Engineering and Biotechnology, University of Chittagong, Chittagong-4331,Bangladesh
  • Md. Jibran Alam Department of Genetic Engineering and Biotechnology, University of Chittagong, Chittagong-4331,Bangladesh
  • Amit Datta Department of Genetic Engineering and Biotechnology, University of Chittagong, Chittagong-4331,Bangladesh
  • Mohammad Al-Forkan Department of Genetic Engineering and Biotechnology, University of Chittagong, Chittagong-4331,Bangladesh

DOI:

https://doi.org/10.3329/cujbs.v9i1.73765

Keywords:

Genotyping, Uropathogenic Escherichia coli (UPEC), Urinary Tract Infection, Virulence factor

Abstract

UropathogenicEscherichia coli are the common cause of Urinary Tract Infection affecting 150 million people each year worldwide. In this study,we investigated the prevalence of UPEC genetic regions coding for various virulence factors.The targeted genetic determinants were those coding for pili associated with pyelonephritis (pap),hemolysin (hly),cytotoxic necrotizing factor (cnf) and aerobactin (aer). We collected 180 urine samples ofUTI patients from the Chittagong region of Bangladesh and isolated UPEC.Among the studied strains the prevalence of pap,hly, cnfand aer genes were 21,25.2,24.3 and 7.0%respectively.This rapid assessment of the bacterial pathogenicity may contribute to a better medical approach for the patients with urinary tract infections.

The Chittagong Univ. J. B. Sci. 9(1&2):39-48,2019

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Published

2024-06-10

How to Cite

Khaleda, L. ., Rudra, B. ., Shawon, I. I. ., Alam, M. J. ., Datta , A. ., & Al-Forkan, M. . (2024). Genotyping of Virulence Factors of Uropathogenic Escherichia Coli from Chittagong, Bangladesh. Chittagong University Journal of Biological Sciences, 9(1), 39–48. https://doi.org/10.3329/cujbs.v9i1.73765

Issue

Vol. 9 No. 1-2 (2019)

Section

Articles