Pharmacological investigation of <i>Areca catechu</i> extracts for evaluation of learning, memory and behavior in rats

Authors

  • Madhusudan Joshi Department of Pharmacology, Faculty of Pharmacy, Goa College of Pharmacy, Panaji Goa
  • Kavita Gaonkar Department of Pharmacology, Faculty of Pharmacy, Goa College of Pharmacy, Panaji Goa
  • Sneha Mangoankar Department of Pharmacology, Faculty of Pharmacy, Goa College of Pharmacy, Panaji Goa
  • Sneha Satarkar Department of Pharmacology, Faculty of Pharmacy, Goa College of Pharmacy, Panaji Goa

DOI:

https://doi.org/10.3329/icpj.v1i6.10533

Keywords:

Areca catechu, Radial arm maze, Memory, Learning

Abstract

Areca catechu Linn is one of the stimulant masticatory crude materials of Indian system of medicine. The present study was done to evaluate the effect of Areca catechu Linn extract on learning and memory in rats using radial arm maze. The extract used for study was of two different types of Areca catechu namely, wet and dried Areca catechu. Three groups of rats each consisting of seven animals were used for the purpose. Test groups were given 500mg/kg p.o of wet Areca catechu extract and dried Areca catechu extract respectively. It was observed that wet Areca catechu extract showed greater increase in spatial memory and learning in comparison to the control group of rats. Hence increase in spatial memory could be because of higher amount of arecoline present in wet Areca catechu extract.

DOI: http://dx.doi.org/10.3329/icpj.v1i6.10533

International Current Pharmaceutical Journal 2012, 1(6): 128-132

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Published

2012-05-06

How to Cite

Joshi, M., Gaonkar, K., Mangoankar, S., & Satarkar, S. (2012). Pharmacological investigation of <i>Areca catechu</i> extracts for evaluation of learning, memory and behavior in rats. International Current Pharmaceutical Journal, 1(6), 128–132. https://doi.org/10.3329/icpj.v1i6.10533

Issue

Vol. 1 No. 6 (2012)

Section

Original Articles

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