Isolation and characterization of novel mucoadhesive biomaterial from Phoenix dactylifera

Authors

  • Abhijeet Ojha DIT, Faculty of Pharmacy, Mussoorie Diversion Road, Dehradun-248009
  • NV Satheesh Madhav DIT, Faculty of Pharmacy, Mussoorie Diversion Road, Dehradun-248009

DOI:

https://doi.org/10.3329/icpj.v1i8.11251

Keywords:

Mucoadhesive polymers, Novel drug delivery, Mucoadhesion, Labial mucosa, Phoenix Dactylifera, Bioadhesion.

Abstract

Phoenix dactylifera belongs to the family Arecaceae. The current aim of our research work is to isolate bio-material from the fruit pulp of Phoenix dactylifera and evaluate its mucoadhesivity. The bio- material was isolated by simple economical process. The isolated biomaterial was subjected for determination of solubility, colour changing point, viscosity, surface tension, pH and chemical tests. The mucoadhesivity of the biomaterial was assessed by shear stress method and rotating cylinder method using Capra aegagrus labium and intestine as mucosal substrates. The results were compared with HPMC and sodium CMC. The research study revealed that the biomaterial from Phoenix dactylifera exhibits promising inbuilt mucoadhesivity. So it can serve as a powerful natural mucoadhesant and may be used to develop mucoadhesive transmucosal drug delivery systems.

DOI: http://dx.doi.org/10.3329/icpj.v1i8.11251

International Current Pharmaceutical Journal 2012, 1(8): 205-208

 

 

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Published

2012-07-05

How to Cite

Ojha, A., & Madhav, N. S. (2012). Isolation and characterization of novel mucoadhesive biomaterial from Phoenix dactylifera. International Current Pharmaceutical Journal, 1(8), 205–208. https://doi.org/10.3329/icpj.v1i8.11251

Issue

Vol. 1 No. 8 (2012)

Section

Original Articles

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