Solid Lipid Nanoparticles (SLN): Method, Characterization and Applications

Authors

  • Akanksha Garud Department of Pharmaceutics, Institute of Professional Studies, College of Pharmacy, Gwalior, Madhya Pradesh 474002
  • Deepti Singh Department of Pharmaceutics, Institute of Professional Studies, College of Pharmacy, Gwalior, Madhya Pradesh 474002
  • Navneet Garud Department of Pharmaceutics, Institute of Professional Studies, College of Pharmacy, Gwalior, Madhya Pradesh 474002

DOI:

https://doi.org/10.3329/icpj.v1i11.12065

Keywords:

Solid lipid nanoparticles, drug delivery, drug incorporation

Abstract

Solid lipid nanoparticles (SLN) have emerged as a next-generation drug delivery system with potential applications in pharmaceutical field, cosmetics, research, clinical medicine and other allied sciences. Recently, increasing attention has been focused on these SLN as colloidal drug carriers for incorporating hydrophilic or lipophilic drugs. Proteins and antigens intended for therapeutic purposes may be incorporated or adsorbed onto SLN, and further administered by parenteral routes or be alternative routes such as oral, nasal and pulmonary. The obstacles associated with conventional chemotherapy may be partially overcome by encapsulating them as SLN. The present review focuses on the utility of SLN in terms of their advantages, production methodology, characterization and applications. If properly investigated, SLNs may open new vistas in therapy of complex diseases.

DOI: http://dx.doi.org/10.3329/icpj.v1i11.12065

International Current Pharmaceutical Journal 2012, 1(11): 384-393

Downloads

Download data is not yet available.
Abstract
398
PDF
280

Downloads

Published

2012-10-03

How to Cite

Garud, A., Singh, D., & Garud, N. (2012). Solid Lipid Nanoparticles (SLN): Method, Characterization and Applications. International Current Pharmaceutical Journal, 1(11), 384–393. https://doi.org/10.3329/icpj.v1i11.12065

Issue

Vol. 1 No. 11 (2012)

Section

Review Articles

License

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).