Anti-fatigue effects of polysaccharides extracted from Rhodiolae Radix

Authors

  • Fenglin Li College of Materials Science and Engineering Yanshan University Qinghuangdao, 066004
  • Furen Xiao College of Materials Science and Engineering Yanshan University Qinghuangdao, 066004
  • Junsheng Qi Institute of Special Animal and Plant Sciences (ISAPS) of Chinese Academy of Agricultural Sciences Jilin, 132109

DOI:

https://doi.org/10.3329/icpj.v2i3.13579

Keywords:

Polysaccharide from Rhodiolae Radix, physical fatigue, forced swimming test, mice

Abstract

The purpose of the present study was to determine the effects of polysaccharide from Rhodiolae Radix (PRR) on physical fatigue using a forced swimming test in male mice. 96 mice were divided randomly into four groups based on body weight (n = 24). One of the groups was the control group; the others were PRR supplemented groups (25, 50 and 100 mg/kg body weight). Forced swimming test of mice were carried out after 28 days of PRR administration, and the blood lactic acid (BLA), blood urea nitrogen (BUN), liver glycogen and muscle glycogen contents were determined. The data suggest that PRR can extend the exhaustive swimming time of the mice, as well as increase the tissue glycogen contents, and decrease the BLA and BUN contents. These results indicated that PRR had significant anti-fatigue effects.

DOI: http://dx.doi.org/10.3329/icpj.v2i3.13579

International Current Pharmaceutical Journal, February 2013, 2(3): 49-52

 

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Author Biography

Fenglin Li, College of Materials Science and Engineering Yanshan University Qinghuangdao, 066004

Jilin Agricultural Science and Technology College

Jilin, 132101, China

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Published

2013-02-02

How to Cite

Li, F., Xiao, F., & Qi, J. (2013). Anti-fatigue effects of polysaccharides extracted from Rhodiolae Radix. International Current Pharmaceutical Journal, 2(3), 49–52. https://doi.org/10.3329/icpj.v2i3.13579

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Original Articles