Evaluation of antidiabetic activity in Corallocarpus epigaeus rhizomes

Authors

  • Kattamanchi Gnananath Department of Pharmacognosy Netaji Institute of Pharmaceutical Sciences Toopranpet, Nalgonda Andhra Pradesh
  • Kontham Ramakanth Reddy Department of Pharmacognosy Netaji Institute of Pharmaceutical Sciences Toopranpet, Nalgonda Andhra Pradesh
  • Gudur Pavan Kumar Department of Pharmacognosy Netaji Institute of Pharmaceutical Sciences Toopranpet, Nalgonda Andhra Pradesh
  • Bheemanapally Krishna Department of Pharmacognosy Netaji Institute of Pharmaceutical Sciences Toopranpet, Nalgonda Andhra Pradesh
  • Karka Srinivas Reddy Department of Pharmacognosy Vaagdevi College of Pharmacy Ramnagar, Hanamkonda Andhra Pradesh
  • Avvari Sanjeeva Kumar Division of Pharmacognosy Raghavendra Institute of Pharmaceutical Education and Research Krishnam Reddy Palli cross Chiyyedu, Anantapur-515721 Andhra Pradesh

DOI:

https://doi.org/10.3329/icpj.v2i3.13581

Keywords:

Corallocarpus epigaeus, herbal medicine, ethanolic extract, phyto constitutes, acute toxicity, haemoglucostrips, flavoniods

Abstract

From these results it can be understood that plant extract showing its pharmacological action on diabetes between the time intervals of 1-2 hr after its administration. This is exactly what the action that is being observed from the standard Glibenclamide group which also shown its action at its 1-2 hr of administration to the animals. Here the statistically significant action of the higher dose of plant extract can be compared with that of the standard Glibenclamide group. From these results it can be understood that the plant extract is capable of inhibiting the elevation of blood glucose level to the extent of the action that has been shown by the standard Glibenclamide group. Particularly at the time interval of 2-4 hr both the Glibenclamide and plant extract at its high dose group that is 400 mg/kg has been significantly inhibited the elevation of the blood glucose levels in the animals.

DOI: http://dx.doi.org/10.3329/icpj.v2i3.13581

International Current Pharmaceutical Journal, February 2013, 2(3): 53-56


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Published

2013-02-02

How to Cite

Gnananath, K., Reddy, K. R., Kumar, G. P., Krishna, B., Reddy, K. S., & Kumar, A. S. (2013). Evaluation of antidiabetic activity in Corallocarpus epigaeus rhizomes. International Current Pharmaceutical Journal, 2(3), 53–56. https://doi.org/10.3329/icpj.v2i3.13581

Issue

Vol. 2 No. 3 (2013)

Section

Original Articles

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