Isolation of astaxanthin from marine yeast and study of its pharmacological activity

Authors

  • Uma Nath Ushakumari Dale View College of Pharmacy and Research Centre Punalal, Trivandrum
  • Ravi Ramanujan Department of Pharmaceutical Chemistry Sankaralingham Bhuvaneswari College of Pharmacy Sivakasi, Tamilnadu

DOI:

https://doi.org/10.3329/icpj.v2i3.13584

Keywords:

Astaxanthin, marine yeast, yeast malt, Antibacterial activity fermentation, well diffusion assay

Abstract

The aim of the present study was to isolate and study about the antibacterial activity of astaxanthin from marine yeast. Astaxanthin a carotenoid present in marine yeast and crustaceans posses a wide range of pharmacological activity. Yeast strain was isolated from the marine sediments collected from Cochin, Kerala during the month of August 2012. The samples were collected in sterile plastic covers and brought to the laboratory without exposing to the external environment further. The marine sediment samples were directly inoculated in yeast malt. After effective screening the strains containing astaxanthin was refrigerated for further use. The strains were purified by TLC using petroleum hexane: acetone (3:1). A spectrophotometric assay was carried out by measuring absorbance at 200-500nm. The antibacterial activity was studied on several organisms like Bacillus Subtilis, Salmonella typhi, Staphylococcus aureus and Pseudomonas aeroginosa. The extracts showed excellent antibacterial activity than the standard chloramphenicol. Among this, Pseudomonas aeroginasa showed maximum inhibition.

DOI: http://dx.doi.org/10.3329/icpj.v2i3.13584

International Current Pharmaceutical Journal, February 2013, 2(3): 67-69

 

Downloads

Download data is not yet available.
Abstract
215
PDF
99

Downloads

Published

2013-02-02

How to Cite

Ushakumari, U. N., & Ramanujan, R. (2013). Isolation of astaxanthin from marine yeast and study of its pharmacological activity. International Current Pharmaceutical Journal, 2(3), 67–69. https://doi.org/10.3329/icpj.v2i3.13584

Issue

Vol. 2 No. 3 (2013)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).