Isolation of astaxanthin from marine yeast and study of its pharmacological activity

Authors

  • Uma Nath Ushakumari Dale View College of Pharmacy and Research Centre Punalal, Trivandrum
  • Ravi Ramanujan Department of Pharmaceutical Chemistry Sankaralingham Bhuvaneswari College of Pharmacy Sivakasi, Tamilnadu

DOI:

https://doi.org/10.3329/icpj.v2i3.13584

Keywords:

Astaxanthin, marine yeast, yeast malt, Antibacterial activity fermentation, well diffusion assay

Abstract

The aim of the present study was to isolate and study about the antibacterial activity of astaxanthin from marine yeast. Astaxanthin a carotenoid present in marine yeast and crustaceans posses a wide range of pharmacological activity. Yeast strain was isolated from the marine sediments collected from Cochin, Kerala during the month of August 2012. The samples were collected in sterile plastic covers and brought to the laboratory without exposing to the external environment further. The marine sediment samples were directly inoculated in yeast malt. After effective screening the strains containing astaxanthin was refrigerated for further use. The strains were purified by TLC using petroleum hexane: acetone (3:1). A spectrophotometric assay was carried out by measuring absorbance at 200-500nm. The antibacterial activity was studied on several organisms like Bacillus Subtilis, Salmonella typhi, Staphylococcus aureus and Pseudomonas aeroginosa. The extracts showed excellent antibacterial activity than the standard chloramphenicol. Among this, Pseudomonas aeroginasa showed maximum inhibition.

DOI: http://dx.doi.org/10.3329/icpj.v2i3.13584

International Current Pharmaceutical Journal, February 2013, 2(3): 67-69

 

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Published

2013-02-02

How to Cite

Ushakumari, U. N., & Ramanujan, R. (2013). Isolation of astaxanthin from marine yeast and study of its pharmacological activity. International Current Pharmaceutical Journal, 2(3), 67–69. https://doi.org/10.3329/icpj.v2i3.13584

Issue

Vol. 2 No. 3 (2013)

Section

Original Articles

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