Pyrethrin from Tanacetum cineriifoliun as repellent against mosquitoes

Authors

  • Peneremmal Amrutha Department of Biotechnology CMS College of Science & Commerce Coimbatore-641 006, Tamil Nadu
  • Balakrishnan Sathya Priya Department of Biotechnology CMS College of Science & Commerce Coimbatore-641 006, Tamil Nadu
  • Shanmugaasokan Lakshmanasenthil Department of Biotechnology CMS College of Science & Commerce Coimbatore-641 006, Tamil Nadu
  • Antonythiraviam Anne Jenifer Department of Biotechnology CMS College of Science & Commerce Coimbatore-641 006, Tamil Nadu
  • Laxmi Satheesh Pillai Department of Biotechnology CMS College of Science & Commerce Coimbatore-641 006, Tamil Nadu
  • Gunasekaran Suja Department of Biotechnology CMS College of Science & Commerce Coimbatore-641 006, Tamil Nadu
  • Thirumalairaj Vinothkumar Department of Biotechnology CMS College of Science & Commerce Coimbatore-641 006, Tamil Nadu

DOI:

https://doi.org/10.3329/icpj.v2i10.16411

Keywords:

Larvicidal assay, irritation, stabilization, toxicity, extracts

Abstract

The present study is conducted to find the efficacy of plant extracts to act as mosquito repellents. Initially, the larvicidal activity of the extracts and the toxicity study was conducted. From the results, the extracts with maximum larvicidal activity and the minimum toxicity were used for the further analysis. The least toxicity was observed with the ethanol extracts of Lantana camara, Tagetes erecta and Tanacetum cineriifolium. The Lanatana camara and Tanacetum cineriifolium showed the maximum larvicidal activity. The DNA sugar damage assay is performed and read at 532 nm. The hemolytic activity of the extract is conducted and the results indicate that the extracts showed no hemolytic activity at the concentration of 100 and 200mg/L. Only the flower extracts of Tagaetes erecta, Lantana camara and Tanacetum cineriifolium showed moderate hemolytic activity at 500 and 1000 mg/L. Finally, the HPLC analysis of the extracts showed that the ethanol extracts of Lantana camara and Tanacetum cineriifloium revealed the presence of marker compound. Therefore the ethanol extracts of Lantana camara and Tanacetum cineriifolium were taken up for the membrane stabilization assay. The skin irritation potential of the cream prepared using the ethanol extract of Tanacetum cineriifolium was analysed, the cream showed no irritation.

DOI: http://dx.doi.org/10.3329/icpj.v2i10.16411

International Current Pharmaceutical Journal, September 2013, 2(10): 170-176

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Published

2013-09-14

How to Cite

Amrutha, P., Priya, B. S., Lakshmanasenthil, S., Jenifer, A. A., Pillai, L. S., Suja, G., & Vinothkumar, T. (2013). Pyrethrin from Tanacetum cineriifoliun as repellent against mosquitoes. International Current Pharmaceutical Journal, 2(10), 170–176. https://doi.org/10.3329/icpj.v2i10.16411

Issue

Vol. 2 No. 10 (2013)

Section

Original Articles

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