Microbicidal activity of crude extracts from Sargassum wightii against Bacillus cereus

Authors

  • Amritha Krishna Bhuvaneshwari Venugopal School of Biological Sciences CMS College of Science & Commerce Coimbatore-641 049 Tamil Nadu
  • Vinoth Kumar Thirumalairaj School of Biological Sciences CMS College of Science & Commerce Coimbatore-641 049 Tamil Nadu
  • Geetharamani Durairaj Department of Microbiology Dr. NGP Arts and Science College Coimbatore-641048 Tamil Nadu
  • Mahitha Puthanpurayal Vijayan School of Biological Sciences CMS College of Science & Commerce Coimbatore-641 049 Tamil Nadu
  • Navya Lazar School of Biological Sciences CMS College of Science & Commerce Coimbatore-641 049 Tamil Nadu
  • Kavya Kurumboor Sathyan School of Biological Sciences CMS College of Science & Commerce Coimbatore-641 049 Tamil Nadu
  • Amrutha Chacko School of Biological Sciences CMS College of Science & Commerce Coimbatore-641 049 Tamil Nadu
  • Rincy Yesudas School of Biological Sciences CMS College of Science & Commerce Coimbatore-641 049 Tamil Nadu
  • Shasna Kadheeja School of Biological Sciences CMS College of Science & Commerce Coimbatore-641 049 Tamil Nadu
  • Ishara Kumari John David School of Biological Sciences CMS College of Science & Commerce Coimbatore-641 049 Tamil Nadu
  • Sezirahiga Jean Damascene School of Biological Sciences CMS College of Science & Commerce Coimbatore-641 049 Tamil Nadu

DOI:

https://doi.org/10.3329/icpj.v3i10.20338

Keywords:

Seaweed, antibacterial activity, pathogen, microbicide, solvents

Abstract

The present study was investigated to explore the antibacterial activity of four different solvent (petroleum ether, chloroform, acetone and ethanol) crude extracts of marine brown seaweed Sargassum wightti. Crude extracts were screened against human pathogen Bacillus cereus. The antibacterial efficiency was performed by agar well diffusion, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) methods. The results revealed that the crude extract of petroleum ether showed prominent inhibiting activity against B. cereus and other crude extracts showed below detectable level. The highest microbicidal activity (zone of inhibition) 9.0 ± 0.32 mm was obtained at the concentration of 250 ?g /ml and the lowest activity was 3 ± 0.20 mm at 31.25 ?g /ml concentration. The MIC and MBC values were found to be 125 and 250 ?g /ml respectively. Results of this study suggested that the compounds present in the crude extracts of petroleum ether showed high activity against B. cereus and further studies are required to purify the active principles.

DOI: http://dx.doi.org/10.3329/icpj.v3i10.20338

International Current Pharmaceutical Journal, September 2014, 3(10): 326-327

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Published

2014-09-05

How to Cite

Venugopal, A. K. B., Thirumalairaj, V. K., Durairaj, G., Vijayan, M. P., Lazar, N., Sathyan, K. K., Chacko, A., Yesudas, R., Kadheeja, S., David, I. K. J., & Damascene, S. J. (2014). Microbicidal activity of crude extracts from Sargassum wightii against Bacillus cereus. International Current Pharmaceutical Journal, 3(10), 326–327. https://doi.org/10.3329/icpj.v3i10.20338

Issue

Vol. 3 No. 10 (2014)

Section

Original Articles

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