Hypoglycemic property of cocoa products: potential underlying mechanisms

Authors

  • Ayad S. Mubarak Clinical Pharmacy Department China Pharmaceutical University Nanjing
  • Tang Yiquen Clinical Pharmacy Department China Pharmaceutical University Nanjing

DOI:

https://doi.org/10.3329/icpj.v4i2.21485

Keywords:

Cocoa flavanols, chocolate, nitric oxide, diabetes mellitus, hypoglycemic

Abstract

Cocoa powder and chocolate is most abundant flavonoids-plant product. Type 2 diabetes mellitus (T2DM) is health and epidemically serious metabolic disorder. The treatment and moreover preventing of T2DM is therapeutic target worldwide. This review focuses on antidiabetic mechanisms of cocoa products. Particularly, intensifying insulin sensitivity, which is a superior pathway for chronic glucose level control, and increasing insulin release for acute glucose level control. Accordingly, the hypoglycemic effect results in elevate synthesis and bioavailability of nitric oxide (NO). Subsequently, improve blood flow and capillary recruitment.

DOI: http://dx.doi.org/10.3329/icpj.v4i2.21485

International Current Pharmaceutical Journal, January 2015, 4(2): 362-366

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Author Biography

Ayad S. Mubarak, Clinical Pharmacy Department China Pharmaceutical University Nanjing

Fallujah Health Sector: Anbar Health Department,

Iraqi Ministry of Health, Anbar

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Published

2015-01-07

How to Cite

Mubarak, A. S., & Yiquen, T. (2015). Hypoglycemic property of cocoa products: potential underlying mechanisms. International Current Pharmaceutical Journal, 4(2), 362–366. https://doi.org/10.3329/icpj.v4i2.21485

Issue

Section

Review Articles