Steroids from the stem of Nymphaea stellata

Authors

  • Badrun Naher Chowdhury Department of Applied Chemistry & Chemical Engineering, University of Dhaka, Dhaka-1000
  • Md Mozammel Haque Herbal Research & Development Department, The ACME Laboratories Ltd., Dhamrai, Dhaka-1350
  • Md Hossain Sohrab Chemical Research Division, Bangladesh Council of Scientific and Industrial Research (BCSIR) Laboratories Dhaka, Dhaka-1205
  • Farhana Afroz Chemical Research Division, Bangladesh Council of Scientific and Industrial Research (BCSIR) Laboratories Dhaka, Dhaka-1205
  • MA Al-Mansur Chemical Research Division, Bangladesh Council of Scientific and Industrial Research (BCSIR) Laboratories Dhaka, Dhaka-1205
  • Tamanna Sultana Department of Applied Chemistry & Chemical Engineering, University of Dhaka Dhaka-1000
  • Choudhury Mahmood Hasan Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000

DOI:

https://doi.org/10.3329/jbas.v37i1.15687

Keywords:

Nymphaeaceae, Nymphaea stellata, Steroids, Antimicrobial activity, Cytotoxicity

Abstract

Three steroids, namely 24-ethyl-5?-cholestan-3-one (1), 5?-stigmast-22-en-3-one (2), stigmast-5, 22-dien-3-one (3) have been isolated from N. stellata. The phytochemical and antimicrobial as well as cytotoxic activities of Nymphaea stellata were investigated in this study. Crude extracts of N. stellata and various column fractions exhibited poor antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria and fungi. The crude extract and the fractions showed significant cytotoxic effect when subjected to brine shrimp lethality bioassay.

DOI: http://dx.doi.org/10.3329/jbas.v37i1.15687

Journal of Bangladesh Academy of Sciences, Vol. 37, No. 1, 109-113, 2013

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Published

2013-07-14

How to Cite

Chowdhury, B. N., Haque, M. M., Sohrab, M. H., Afroz, F., Al-Mansur, M., Sultana, T., & Hasan, C. M. (2013). Steroids from the stem of Nymphaea stellata. Journal of Bangladesh Academy of Sciences, 37(1), 109–113. https://doi.org/10.3329/jbas.v37i1.15687

Issue

Vol. 37 No. 1 (2013)

Section

Short Communication