Association of serum zinc and vitamin E levels with Acne vulgarisin Bangladeshi acne patients

Authors

  • Tania Sultana Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh
  • Aklima Akter Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh
  • Fatima Tuz Zohra Department of Pathology, Central Police Hospital, Dhaka, Bangladesh
  • Md Quddusur Rahman Department of Clinical Pathology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Yearul Kabir Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jbas.v45i1.54259

Keywords:

Zinc, Vitamin E, Acne vulgaris, Bangladeshi population, Acne treatment

Abstract

The serum level of zinc and vitamin E were measured to understand the association of various nutrients on acne pathogenesis. Both zinc and vitamin E are antioxidants used as a supplement in acne treatment. However, their effect and status in acne patients are not fully understood. This study included 48 acne patients and 48 sex- and age-matched healthy controls. The zinc and vitamin E concentration was measured in the serum by flame atomic absorption spectroscopy (AAS) and HPLC methods. Compared to the healthy control, a significant deficiency of serum vitamin E level in acne patients (p<0.001) was found, although the patients were not deficient in serum zinc level (p=0.22). In addition, female acne patients had a slightly lower zinc level than male patients (p=0.06). The low serum vitamin E level suggests that supplementation of vitamin E might be helpful in acne treatment. However, further studies are required to understand the dose and mechanism of vitamin E supplements in acne treatment.

J. Bangladesh Acad. Sci. 45(1); 49-58: June 2021

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Published

2021-07-15

How to Cite

Sultana, T., Akter, A., Zohra, F. T., Rahman, M. Q., & Kabir, Y. (2021). Association of serum zinc and vitamin E levels with Acne vulgarisin Bangladeshi acne patients. Journal of Bangladesh Academy of Sciences, 45(1), 49–58. https://doi.org/10.3329/jbas.v45i1.54259

Issue

Section

Research Articles