Stereoselectivity of thiazolidine, malonamides and bicyclic tetramates with isopropyl NH and SH protecting group

Authors

  • Halima Bagum Department of Chemistry, University of Barishal, Bangladesh
  • Mark G Moloney Department of Chemistry, University of Oxford, United Kingdom

DOI:

https://doi.org/10.3329/jbas.v47i2.66977

Keywords:

tetramate, cyclization, heterocycle, stereoselectivity

Abstract

The stereochemistry of the routes to two different bicyclic tetramates are reported which enables to synthesize highly functionalized systems. An analysis of the structure shows that the tetramates permit ready incorporation of three to five functionality at different positions. This work demonstrates that novel bicyclic tetramates can be synthesized via stereoselective cyclization. The resulting heterocycles were studied with the help of NMR techniques.

J. Bangladesh Acad. Sci. 47(2); 215-222: December 2023

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Published

2023-12-21

How to Cite

Bagum, H. ., & Moloney, M. G. (2023). Stereoselectivity of thiazolidine, malonamides and bicyclic tetramates with isopropyl NH and SH protecting group. Journal of Bangladesh Academy of Sciences, 47(2), 215–222. https://doi.org/10.3329/jbas.v47i2.66977

Issue

Section

Research Articles