Leptin, the Creation of Obesity Gene and its task in Pregnancy

Authors

  • Shakeela Ishrat Junior Consultant of Gynecology & Obstetrics, Brahmanbaria Sadar Hospital Brahmanbaria
  • Md Zahid Hussain Associate Professor of Pediatrics, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka
  • Sultana Jahan Chairman and Head (Ex), Department of Gynecology & Obstetrics, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka

DOI:

https://doi.org/10.3329/jbsp.v3i0.1803

Keywords:

Leptin, Adipose tissue, Placenta, Fetus, Growth

Abstract

Leptin is a protein encoded by the âob' gene. Leptin is primarily produced by adipocytes and its primary physiologic function is to suppress body fat. Obese individuals have high serum leptin levels and obesity is a leptin resistant state. There are evidences that leptin levels are higher in pregnant women compared to non pregnant women. Leptin levels increase as pregnancy advances and at term, approximate those found in obese adults. There is speculation that leptin is synthesized in placenta in addition to adipose tissue mass. Leptin may have a permissive, indirect role in regulation of fetal growth.

Key Words: Leptin, Adipose tissue, Placenta, Fetus, Growth  

doi: 10.3329/jbsp.v3i0.1803  

J Bangladesh Soc Physiol.2008 Dec;(3):79-84.

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How to Cite

Ishrat, S., Hussain, M. Z., & Jahan, S. (2009). Leptin, the Creation of Obesity Gene and its task in Pregnancy. Journal of Bangladesh Society of Physiologist, 3, 79–84. https://doi.org/10.3329/jbsp.v3i0.1803

Issue

Vol. 3 (2008)

Section

Review

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