Diabetic Cardiac Autonomic Dysfunction and Its Relationship with Duration of Diabetes

Authors

  • - Phurpa MD resident, Dept of Physiology, Bangabandhu Sheikh Mujib, Medical University, Shahbag, Dhaka
  • Sultana Ferdousi Associate Professor, Dept of Physiology, Bangabandhu Sheikh Mujib, Medical University, Shahbag, Dhaka

DOI:

https://doi.org/10.3329/jbsp.v11i1.29702

Keywords:

HRV, SDNN, T2DM

Abstract

Background: Duration of diabetes may have an important influence on cardiac autonomic dysfunction in type 2 diabetes mellitus.

Objective: To assess the relationship of cardiac autonomic dysfunction in type 2 diabetes mellitus(T2DM) with the duration of diabetes.

Methods: This crosssectional study was carried out from January to December 2015 on 54 long-term T2DM male patients aged 45 to 55 years, selected from the Endocrinology OPD of BSMMU, Dhaka. Thirty age matched recently diagnosed male T2DM patients(RT2DM) were control. Cardiac autonomic function was assessed by Heart Rate Variability(HRV). HRV measures were obtained by RMS multi channel polyrite-D. For statistical analysis, unpaired t-test and Pearsons correlation coefficient test were used.

Results: Mean RR, SDNN, and HF nu were significantly lower (p < 0.001) whereas, mean HR, LF nu and LF/HF were significantly (p < 0.001) higher in LT2DM than those of RT2DM. SDNN, RMSSD and variance showed significant (p < 0.001) negative correlation with the duration of diabetes.

Conclusions: Duration of diabetes had strong negative relationship with the diabetic cardiac autonomic dysfunction.

Bangladesh Soc Physiol. 2016, June; 11(1): 1-5

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Author Biography

- Phurpa, MD resident, Dept of Physiology, Bangabandhu Sheikh Mujib, Medical University, Shahbag, Dhaka



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Published

2016-09-24

How to Cite

Phurpa, .-., & Ferdousi, S. (2016). Diabetic Cardiac Autonomic Dysfunction and Its Relationship with Duration of Diabetes. Journal of Bangladesh Society of Physiologist, 11(1), 1–5. https://doi.org/10.3329/jbsp.v11i1.29702

Issue

Vol. 11 No. 1 (2016)

Section

Articles

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