PEFR and FEF<sub>25-75</sub> in type 2 diabetes mellitus and their relationships with its duration

Authors

  • Md Omar Ali Assistant professor, Department of Physiology, Jahurul Islam Medical College (JIMC), Kishoregonj
  • Shelina Begum Professor & Chairman, Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU)
  • Noorzahan Begum Professor & Former Chairman, Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU)
  • Taskina Ali Assistant Professor, Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU)
  • Sultana Ferdousi Assistant Professor, Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU)

DOI:

https://doi.org/10.3329/jbsp.v5i1.5413

Keywords:

PEFR, FEF25-75, Diabetes Mellitus.

Abstract

Background: Diabetes mellitus is a major public health problem with increasing incidence worldwide
and long term complications of various organs including lungs. The magnitude of the complications
of this disease is related to its duration. Objective: To observe PEFR and FEF25-75 in type 2 diabetic
male and their relationship with duration of the disease. Methods: This cross sectional study was
carried out in the Department of Physiology, BSMMU, Dhaka, from 1st July 2007 to 30th June 2008 on
60 type 2 diabetic, non smoker, male of 40-60 years old. For comparison, 30 age, BMI and socioeconomic
status matched apparently healthy non diabetic subjects were also studied. Based on the duration of
disease, diabetic patients were divided into B1 (5-10 years) and B2 (10-20 years). PEFR and FEF25-75 of
all the subjects were measured by an electronic spirometer. Data were analyzed by One way ANOVA,
Unpaired Student's 't' and Pearson's correlation coefficient tests. Results: The mean percentage of
predicted values of PEFR and FEF25-75 in non diabetic male were within normal ranges. But, both the
parameters were significantly (p<0.001) lower in both the groups of type 2 diabetic male compared to
those of non diabetic male. Again, the PEFR and FEF25-75 were lower in the patients of longer duration
compared to those of shorter duration but the differences were not significant. However, PEFR was
negatively correlated and FEF25-75 was positively correlated with shorter duration of diabetes and the
relationships were nonsignificant. On the other hand, both the parameters were negatively correlated
with longer duration of diabetes while only PEFR showed significant (p<0.01) relationship. Conclusion:
The PEFR and FEF25-75 may be lower in type 2 diabetic male, which are inversely related to the
duration of the disease.


Key words: PEFR; FEF25-75; Diabetes Mellitus.

DOI: 10.3329/jbsp.v5i1.5413

J Bangladesh Soc Physiol. 2010 June; 5(1): 14-19

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How to Cite

Ali, M. O., Begum, S., Begum, N., Ali, T., & Ferdousi, S. (2010). PEFR and FEF<sub>25-75</sub> in type 2 diabetes mellitus and their relationships with its duration. Journal of Bangladesh Society of Physiologist, 5(1), 14–19. https://doi.org/10.3329/jbsp.v5i1.5413

Issue

Vol. 5 No. 1 (2010)

Section

Articles

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