Clinical Features of Choledocholithiasis Patientsan Observational Study

Abstract

Background: Choledocholithiasis is a prevalent biliary condition resulting from stones in the common bile duct (CBD), resulting in blockage and issues like cholangitis and pancreatitis. Diagnosis depends on clinical, laboratory, and imaging results, with endoscopic retrograde cholangiopancreatography (ERCP) being the main treatment. This research sought to evaluate the clinical characteristics, laboratory results, and outcomes of patients with choledocholithiasis in Bangladesh. Methods: An observational study based in a hospital was carried out at BSMMU, Dhaka, from July to December 2024, involving 80 adult patients with confirmed choledocholithiasis diagnosed via clinical, laboratory, and imaging results. Information regarding clinical features, laboratory profiles, imaging traits, treatment methods, and outcomes were gathered and examined utilizing SPSS version 25.0. Approval from an ethics committee and informed consent were secured. Results: In a group of 80 patients with choledocholithiasis, the average age was 49.6 ± 14.1 years, with a higher proportion of females (58.8%). Right upper quadrant pain (92.5%), jaundice (68.8%), and elevated ALP (80%) were the predominant findings. CBD dilatation was observed in 82.5%, while ERCP achieved a 92.5% stone clearance rate with favorable outcomes. Larger stones (>10 mm) were significantly associated with acute cholangitis (p=0.024), highlighting the importance of early diagnosis and appropriate management. Conclusion: Choledocholithiasis frequently impacted middle-aged women and manifested as right upper quadrant discomfort, jaundice, and liver function irregularities. ERCP resulted in significant stone removal, whereas larger CBD stones heightened the risk of acute cholangitis, highlighting the importance of prompt diagnosis and treatment.

Journal of Paediatric Surgeons of Bangladesh (2026) Vol. 17 (2): 76-81