Prevalence and Associated Factors of Helicobacter pylori Infection Among Symptomatic AdultsUndergoing Upper Gastrointestinal Endoscopy in Bangladesh: A Single-Center Cross-Sectional Study

Authors

  • Mahedi Hasan Senior Consultant and Head, Department of Gastroenterology and Hepatology, Central Police Hospital, Dhaka, Bangladesh https://orcid.org/0009-0007-7858-6522
  • Fatema Tuz Zohora Sonya Junior Consultant, Department of Medicine, Central Police Hospital, Dhaka, Bangladesh
  • Mahir Washif Rafi Medical Officer, Department of Gastroenterology and Hepatology, Central Police Hospital, Dhaka, Bangladesh https://orcid.org/0009-0006-9524-8392
  • S M Saad Morshed Medical Officer, Department of Internal Medicine, Central Police Hospital, Dhaka, Bangladesh https://orcid.org/0009-0007-0392-2579
  • Rakiba Assistant Registrar, Department of Gastroenterology and Hepatology, Central Police Hospital, Dhaka, Bangladesh https://orcid.org/0009-0009-4096-1774
  • Suef Mahamud Midad Medical Officer, Gastroenterology & Haepatology, Central Police Hospital, Dhaka, Bangladesh
  • Mohammad Syedul Islam Associate Professor, Department of Internal Medicine, Bangladesh Medical University, Dhaka, Bangladesh. https://orcid.org/0009-0001-1390-0628

Keywords:

Risk Factor., Upper Gastrointestinal Endoscopy, Gastrointestinal Endoscopy, Helicobacter pylori Infection, Prevalence

Abstract

Background: Helicobacter pylori is a Gram-negative bacterium associated with gastritis, peptic ulcer disease, gastric cancer, and MALT lymphoma. It is transmitted mainly through oral–oral and fecal–oral routes and can be diagnosed using urea breath tests, stool antigen tests, serological methods, and endoscopic gastric biopsy-based tests. This study evaluated the proportion of H. pylori infection and its associated factors among symptomatic adults undergoing upper gastrointestinal (UGI) endoscopy. Methods: A cross-sectional study was conducted in 2025 among 140 consecutive symptomatic adults undergoing UGI endoscopy at a hospital. Gastric biopsy rapid urease testing (RUT) was used to assess H. pylori infection status. Sociodemographic and clinical risk factors were assessed through structured questionnaires and health records. Data were analyzed using SPSS version 26. Ethical approval and informed consent were obtained. Results: Among 140 symptomatic adults undergoing UGI endoscopy, H. pylori infection was detected in 60.0% of participants. Infection was significantly associated with gastritis and was particularly frequent among patients with duodenal ulcers (90.0%) and gastric ulcers (75.0%) (p < 0.001). Multivariable analysis identified current smoking (AOR = 2.64), rural residence (AOR = 2.31), and male sex (AOR = 1.92) as independent predictors of H. pylori infection. Conclusion: Among symptomatic adults undergoing UGI endoscopy, H. pylori infection was common, being detected in 60.0% of participants, and was strongly associated with gastritis and peptic ulcer disease. Male sex, rural residence, and current smoking were independent predictors of infection. These findings highlight the importance of targeted detection and eradication strategies among symptomatic patients undergoing UGI endoscopy.

Journal of Paediatric Surgeons of Bangladesh (2026) Vol. 17 (2): 46-51

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Published

2026-09-23

Issue

Vol. 17 No. 2 (2026)

Section

Original Articles

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How to Cite

Hasan, M., Sonya, F. T. Z. ., Rafi, M. W. ., Morshed, S. M. S., Rakiba, Midad, S. M., & Islam, M. S. (2026). Prevalence and Associated Factors of Helicobacter pylori Infection Among Symptomatic AdultsUndergoing Upper Gastrointestinal Endoscopy in Bangladesh: A Single-Center Cross-Sectional Study. Journal of Paediatric Surgeons of Bangladesh, 17(2), 46-51. https://doi.org/10.3329/jpsb.v17i2.92969