Effect of Ashwagandharishta on the lipid profile of male and female rats

Authors

  • Tasmina Rahman Department of Pharmacy, Jahangirnagar University, Savar, Dhaka- 1342, Bangladesh
  • Mohammad Salahuddin Bhuiya Department of Pharmacy, Jahangirnagar University, Savar, Dhaka- 1342, Bangladesh
  • Rakib Hasan Department of Pharmacy, Jahangirnagar University, Savar, Dhaka- 1342, Bangladesh
  • MSK Choudhuri Department of Pharmacy, Jahangirnagar University, Savar, Dhaka- 1342, Bangladesh

DOI:

https://doi.org/10.3329/jujbs.v9i1-2.53707

Keywords:

Ashwagandharishta, Serum Cholesterol, HDL, LDL and Triglyceride

Abstract

The effect of Ashwagandharishta on the lipid profile and chronic toxicity of both male and female Albino rats were observed for 51 days. Our results demonstrate that the treatment of the plant extract failed to exhibit any statistically significant change (increase/ decrease) in the serum cholesterol (Total), high density lipoprotein (HDL), low density lipoprotein (LDL) and triglyceride of the male rats. But the female rats showed highly (p<0.01) and very highly (p<0.001) significant decrease in the serum cholesterol (Total) levels of the medium and high dose treated groups respectively. Regarding HDL, ASG showed statistically significant decrease at low (p <0.05), medium (p<0.01) and high (p<0.001) dose treated female rats. The LDL level of the medium dose treated female rats were statistically significant (p <0.05). The serum Triglyceride decreased significantly at low (p<0.01) and high (p <0.05) dose treated female rats.

Jahangirnagar University J. Biol. Sci. 9(1 & 2): 59-68, 2020 (June & December)

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Published

2021-06-01

How to Cite

Rahman, T., Bhuiya, M. S., Hasan, R., & Choudhuri, M. (2021). Effect of Ashwagandharishta on the lipid profile of male and female rats. Jahangirnagar University Journal of Biological Sciences, 9(1-2), 59–68. https://doi.org/10.3329/jujbs.v9i1-2.53707

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Section

Original Research Articles