Effect of traditional medicinal plants on the pathogenic potential of the versatile pathogen Staphylococcus aureus

Authors

  • Aparna Shil Department of Botany, Faculty of Biological Sciences, Jahangirnagar University, Savar, Dhaka – 1342, Bangladesh
  • Md Nazmussakib Shuvo Department of Botany, Faculty of Biological Sciences, Jahangirnagar University, Savar, Dhaka – 1342, Bangladesh
  • Habiba Sultana Department of Botany, Faculty of Biological Sciences, Jahangirnagar University, Savar, Dhaka – 1342, Bangladesh
  • Nuhu Alam Department of Botany, Faculty of Biological Sciences, Jahangirnagar University, Savar, Dhaka – 1342, Bangladesh
  • Mahbubul Kabir Himel Department of Botany, Faculty of Biological Sciences, Jahangirnagar University, Savar, Dhaka – 1342, Bangladesh

DOI:

https://doi.org/10.3329/jujbs.v12i1.74475

Keywords:

medicinal plants

Abstract

This study explores the effects of Neem (Azadirachta indica) and Papaya (Carica papaya) leaf extracts on the pathogenicity of Staphylococcus aureus. Through in vitro assays, we investigated the impact of these medicinal plant extracts on bacterial metabolic activity and pathogenic factors. Results indicate that the growth of Staphylococcus aureus was differentially decreased by the plant extracts, with Neem demonstrating a greater reduction compared to Papaya. Moreover, both Neem and Papaya extracts, either alone or in combination, significantly inhibited bacterial biofilm formation, with reductions of 39%, 48%, and 7%, respectively. Both aqueous and ethanolic extracts exhibited inhibitory effects on bacterial growth, with ethanolic extract showing stronger potency. However, the extracts did not influence the bacteria's haemolytic characteristics. Overall, these findings suggest that traditional medicinal plant extracts possess potential in mitigating S. aureus pathogenicity, however, further mechanistic investigations are warranted to elucidate underlying mechanisms.

Jahangirnagar University J. Biol. Sci. 12(1 & 2): 73-86, 2023 (June & December)

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Published

2024-06-26

How to Cite

Shil, A. ., Shuvo, M. N. ., Sultana, H. ., Alam, N. ., & Himel, M. K. . (2024). Effect of traditional medicinal plants on the pathogenic potential of the versatile pathogen Staphylococcus aureus. Jahangirnagar University Journal of Biological Sciences, 12(1), 73–86. https://doi.org/10.3329/jujbs.v12i1.74475

Issue

Vol. 12 No. 1-2 (2023)

Section

Original Research Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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Articles in the Jahangirnagar University Journal of Biological Sciences are Open Access articles published under the Creative Commons CC BY License (https://creativecommons.org/licenses/by/4.0/). This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.