Pattern of upper GlT lesions diagnosed by histopathological examination of endoscopic biopsies in a rural tertiary hospital

Abstract

Background: There are many benign and malignant lesions occur in upper gastrointestinal tract (GIT). Endoscopic biopsy followed by histopathological examination is the gold standard for the diagnosis of these lesions.

Objectives: The aim of this study was to determine patterns of benign and malignant lesionsof upper GIT.

Materials & Methods: This was a retrospective study carried out in the department of Pathology, Khwaja Yunus Ali Medical College & Hospital (KYAMCH), Sirajgonj from January 2014 to December 2016. All the upper GIT endoscopic biopsy specimens were included in the study.

Results: A total of 344 endoscopic biopsies are studied, of which male cases were 234 (68.0%) and female were 110 (32.0%) with M: F of 2.1:1. The age (mean ± sd) of patients was 53.29 ± 15.33 years. Stomach was the most frequent site (77.9%) followed by oesophagus (16.8%) and duodenum (5.3%). The significant diagnostic findings showed malignancies 190(55.2%) followed by inflammation 73 (21.2%) and ulcer 33 (9.6%).

Conclusion: For any suspicious lesions in upper GIT, endoscopy followed by histopathological examination should be done for early diagnosis as well as management.

KYAMC Journal Vol. 9, No.-1, April 2018, Page 20-23