EFFECTS OF CHRONIC ARSENIC TOXICITY ON THE HAEMATOLOGY AND HISTOARCHITECTURE OF FEMALE REPRODUCTIVE SYSTEM OF BLACK BENGAL GOAT

Abstract

This study was aimed to observe the effects of chronic arsenic toxicity on the haematology and histoarchitecture of female reproductive system of black Bengal goat. Adult She goats (N=4) were orally administered with sodium arsenite (4 mg/kg body weight) for first seven weeks followed by 5 mg/kg body weight for next eight weeks. Blood was collected from the treated goat at day0, 20, 40, 60, 80 and 100. There was significant difference of TEC, Hb concentration and TLC in goats which are chronically exposed with arsenic. Lymphocyte was decreased with the treatment of sodium arsenite but neutrophil, eosinophil and monocyte were increased. At the end of study the goats were euthanasized. The ovary, uterine tube, uterus, cervix and vagina were collected for gross and histopathological examinations. In histopathological examination the ovarian follicles appeared degenerated and there was much stromal thickening around the follicle. Thickened myometrial layer and shortened mucosal folds in the uterine tube were observed. There was reduction in the number and size of endometrial glands. The mucosal cell lines appeared degenerated. Thin vaginal mucosa and proliferation of connective tissue; shortened cervical crypts and thickened glandular epithelium of cervix were also observed. It may be concluded that chronic arsenic exposure might have adverse effects on the female reproductive system.

DOI = http://dx.doi.org/10.3329/bjvm.v9i1.11214

Bangl. J. Vet. Med. (2011). 9(1): 59-66