Effects of Butter on Blood Biochemistry and Histotexure of Heart in the Development of Obesity in Swiss Albino Mice

Authors

  • MS Islam School of Agriculture and Rural Development, Bangladesh Open University, Gazipur-1705
  • MK Islam Department of Physiology, Bangladesh Agricultural University, Mymensingh-2202
  • SK Das Department of Anatomy and Histology, Bangladesh Agricultural University, Mymensingh-2202
  • MM Hossain Department of Anatomy, Histology and Physiology, Sher-e-Bangla agricultural University, Sher-e- Bangla Nagar, Dhaka-1207

DOI:

https://doi.org/10.3329/bjvm.v12i2.21293

Keywords:

Mice, Obesity, Butter, Hypercholesterolemia, Hypocholesterolemia

Abstract

The study was designed and performed in order to investigate the effects of butter on blood biochemistry and histo-texture of heart in mice. Thirty days old 30 Swiss Albino mice were divided into 3 equal groups (M, M1, and M2). Mice of group M were fed with normal mice pellet and were designated as control. Mice in the group M1 and M2 were fed with 10% and 20% butter supplemented feed respectively. In biochemical study, group M2 showed increase in total plasma cholesterol (P<0.001), LDL (P<0.001), TG (P<0.001), blood glucose (P<0.05), blood urea nitrogen (P<0.05) compared to mice in control group. In group of M1 there were also increase in total plasma cholesterol (P<0.01), LDL (P<0.001), TG (P<0.001), blood glucose (P<0.05), blood urea nitrogen (P<0.05) compared to mice in control group but lesser increased than the mice fed with 20% butter supplemented feed. In histopathological study there was no significant change in the heart of mice.

DOI: http://dx.doi.org/10.3329/bjvm.v12i2.21293

Bangl. J. Vet. Med. (2014). 12 (2): 203-209

 

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Published

2014-12-24

Issue

Vol. 12 No. 2 (2014)

Section

Laboratory Animal Medicine