EFFICACY OF OXYTETRACYCLINE, AMOXICILLIN, SULFAMETHOXAZOLE AND TRIMETHOPRIM, AND TYLOSIN FOR THE TREATMENT OF BACTERIAL DISEASES IN CATTLE AND GOATS

Abstract

A single blind clinical trial was carried out in Satkhira district where dairy operations by Community-based Dairy Veterinary Foundation,BangladeshAgriculturalUniversity, Mymensingh were running. A total of 80 cattle and goats affected with different bacterial diseases were used for treatment with oxytetracycline, amoxicillin, combined preparation of sulfamethoxazole and trimethoprim, and tylosin. Diagnosis of diseases was based on clinical history and signs. Haemorrhagic septicemia (HS) affected cattle aged between 3 and 6 were treated with oxytetracycline (Tetravet-100,Acme,Bangladesh; DUFA-OTC 20% LA, DutchFarm,Holland). Amoxicillin (Amoxicillin trihydrate, Jickstar Pharma Inc.,Philippines; Moxilin Vet LA, The ACME Laboratories Ltd.,Bangladesh) was used in the treatment of calf pneumonia. Foot rot in cows, arthritis in calf and goat were treated with sulphamethoxazole and trimethoprim (Politrim-Vet, The ACME Laboratories Ltd.,Bangladesh). Bronchopneumonia in non-lactating cows and goats were treated with tylosin (Tylovet (Acme). The efficacy of oxytetracycline, amoxicillin, sulfamethoxazole and trimethoprim, and tylosin for the treatment of haemorrhagic septicemia, calf pneumonia, foot rot and bronchopneumonia were evaluated on the basis of recovery rate. Treatment of haemorrhagic septicemia with both antibiotics showed 100% recovery rate. The duration of complete recovery in Tetravet-100 treated group was 4-6 days with median of 5 days. In the DUFA-OTC 20% LA treated group it was 3-5 days with median of 4 days. Moxilin Vet® (Acme) and Amoxicillin trihydrate® (Jickstar Pharma) were evaluated against calf pneumonia in cattle. Cent percent cattle were cured with both the antibiotics, Moxilin Vet® (Acme) and Amoxicillin trihydrate® (Jickstar Pharma). For both antibiotics, the median days of complete recovery was 5. Of 5 foot rot affected cows treated with a combined preparation of sulfamethoxazole and trimethoprim (Politrim-Vet®, Acme), 4 (80%) recovered within 4-5 days of treatment. However, treatment of arthritis affected calf and goat with same preparation showed 90% and 100% recovery rate, respectively. Treatment of bronchopneumonia cases with tylosin (Tylovet®, Acme) resulted in 80% recovery in non-lactating cows and 90% in goats and it took 4-5 days for recovery with a median of 4 days.