COMPARATIVE IMMUNOGENICITY OF BIOTYPHOID<sup>&reg;</sup> AND DLS PREPARED FOWL TYPHOID VACCINE IN LAYER CHICKENS

Authors

  • J Ferdous Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202
  • MSR Khan Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202
  • F Begum Veterinary Training Institute, Khakdahor, Mymensingh
  • J Hassan Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202
  • B Sarker Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202

DOI:

https://doi.org/10.3329/bjvm.v8i1.7394

Keywords:

Comparative, immunogenicity, DLS, fowl typhoid, vaccine, BIO-TYPHOID<sup>&reg, </sup>

Abstract

The experiment was conducted to investigate the immunogenicity of DLS prepared Fowl typhoid vaccine in comparison to commercially available BIO-TYPHOID® (Imported by Advance Animal Science Co. Ltd., Bangladesh) in layer chickens. To compare the immunogenicity of these two vaccines a total of 30 chickens were divided into three groups (group A, B and C) each including 10 layer chickens of Fayoumi breed. Chickens of group A and B were vaccinated with DLS prepared fowl typhoid vaccine and BIO-TYPHOID® respectively following usual schedule of vaccination (i.e. first dose at 42 days of age and second dose at 72 and 112 days for DLS prepared fowl typhoid vaccine and BIO-TYPHOID® respectively) with a dose of 0.5 ml at each occasion through SC route. Birds of group C were kept as unvaccinated control. Blood samples were collected to obtain sera from each chicken at every 7 days interval up to 105 days post vaccination for determination of antibody titre following primary and secondary vaccination using Microplate Agglutination test. Highest mean antibody titres obtained from Group A and B which were 460.80 and 409.60 respectively. Among the chickens vaccinated the highest mean antibody titre of 460.80 was obtained at 56 days post vaccination from chickens in group A vaccinated with DLS prepared Fowl typhoid vaccine. Results of this study revealed that DLS prepared fowl typhoid vaccine induced higher antibody production than BIO-TYPHOID®.

 

DOI = 10.3329/bjvm.v8i1.7394

Bangl. J. Vet. Med. (2010). 8(1): 01-04

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Avian Medicine