Risk Factors and Primary Diseases Responsible for Acute Kidney Injury among Neonates

Authors

  • Sharmin Akter Luna Post-Graduate on Paediatric Nephrology, Department of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Syma Akter Post Graduate on Obstetrics & Gynecology (On Deputation), Department of Obstetrics & Gynecology, Sir Salimullah Medical College& Mitform Hospital, Dhaka
  • Tahmina Jesmin Assistant Professor, Department of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Syed Saimul Haque Associate Professor, Department of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Golam Muin Uddin Professor & Former Chairman, Department of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Ranjit Ranjan Roy Professor & Chairman, Department of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka

DOI:

https://doi.org/10.3329/jcamr.v8i1.52475

Keywords:

Risk factors, primary diseases, acute kidney injury, neonates

Abstract

Background: There are several risk factors and diseases related with the acute kidney injury among neonates.

Objective: The purpose of the present study was to find out the risk factors and primary disease responsible for acute kidney injury among neonates.

Methodology: This cross-sectional study was conducted in the Department of Paediatric Nephrology at Bangabandhu Sheikh Mujib University, Dhaka, Bangladesh from May 2018 to July 2019 for a period of one year. Patients with the age group of less than 1 months who were at risk of AKI, and admitted in the inpatient department of Pediatrics and allied at Bangabandhu Sheikh Mujib University, Dhaka, Bangladesh in both sexes were selected as study population. To detect AKI, serum creatinine was measured at 0 h (baseline), 48 h and 5th day respectively.

Result: A total number of 52 patients who fulfilled the inclusion criteria were enrolled in this study. Among them 10 cases were in neonatal age group. The mean age was 10.8±5.4 days with female predominance. The risk factors of AKI in neonate was only pre-renal; mostly due to hypovolemia which was 3(60.0%) cases followed by sepsis and asphyxia which were 1(20.0%) case in each. The most patients had sepsis which was 4(40.0%) cases followed by congenital heart disease which was 2(20.0%) cases; one presented with heart failure and another one had cyanotic congenital heart disease.

Conclusion: In conclusion hypovolemia, sepsis and asphyxia are the most common risk factors of acute kidney injury among the neonates.

Journal of Current and Advance Medical Research, January 2021;8(1):12-16

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Published

2021-03-15

How to Cite

Luna, S. A., Akter, S., Jesmin, T., Haque, S. S., Uddin, G. M., & Roy, R. R. (2021). Risk Factors and Primary Diseases Responsible for Acute Kidney Injury among Neonates. Journal of Current and Advance Medical Research, 8(1), 12–16. https://doi.org/10.3329/jcamr.v8i1.52475

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Original Articles