Screening of Antimicrobial and Antioxidant Properties of Ethylenediamine Mono-dithiocarbamate to Overcome the Resistance of Microbes Against Existing Drugs

A Sarker; M Irfan Ali; T T  Arzina; M Lokman Hossain; M Aminul Haque; A K M  Lutfor Rahman

doi:10.3329/jscitr.v4i1.67380

Screening of Antimicrobial and Antioxidant Properties of Ethylenediamine Mono-dithiocarbamate to Overcome the Resistance of Microbes Against Existing Drugs

Authors

A Sarker Department of Chemistry, Jagannath University, Dhaka-1100
M Irfan Ali Department of Chemistry, Jagannath University, Dhaka-1100
T T Arzina Dhaka City International College, Dhaka-1217
M Lokman Hossain Department of Chemistry, Jagannath University, Dhaka-1100
M Aminul Haque Department of Chemistry, Jagannath University, Dhaka-1100
A K M Lutfor Rahman Department of Chemistry, Jagannath University, Dhaka-1100

DOI:

https://doi.org/10.3329/jscitr.v4i1.67380

Keywords:

Ethylenediamine Mono-dithiocarbamate; Antibacterial; Antifungal and Antioxidant activity

Abstract

Excellency of the medical treatment depends on the potentiality of drugs. The increase of the resistance of microbes against drugs is influencing this aspect. Dithiocarbamate has an application in medicine and biology. Therefore, we have synthesized ethylenediamine mono-dithiocarbamate ligand and explored its antimicrobial and antioxidant property. The ligand exhibited moderate antibacterial activity against 13 (thirteen) selected bacteria in disk diffusion method. It showed notable antifungal activity compared to the standard. Therefore, this ligand may be considered as a potential antifungal agent in antifungal drug design. The antioxidant behavior using DPPH assay revealed that this ligand has significant capability in scavenging radicals as compared to standard.

J. of Sci. and Tech. Res. 4(1): 183-190, 2022

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Published

2023-07-03

How to Cite

Sarker, A., Ali, M. I., Arzina, T. T. ., Hossain, M. L., Haque, M. A., & Lutfor Rahman, A. K. M. . (2023). Screening of Antimicrobial and Antioxidant Properties of Ethylenediamine Mono-dithiocarbamate to Overcome the Resistance of Microbes Against Existing Drugs. Journal of Science and Technology Research, 4(1), 183–190. https://doi.org/10.3329/jscitr.v4i1.67380