Studies on Antifungal Activity and Brine Shrimp Toxicity Argemone mexicana

Authors

  • Ainun Nahar Lecturer, Department of Pharmacology, Rajshahi Medical College, Rajshahi
  • Anwar Habib Professor & Head, Department of Pharmacology, Rajshahi Medical College, Rajshahi
  • MA Awal Professor & Head, Department of Pharmacology, North Bengal Medical College, Sirajgonj
  • AKM Shahidur Rahman Assistant Professor, Department of Pharmacology, KYAMC, Enayetpur, Sirajgonj
  • MA Gafur Mondal Professor & Head, Department of Blood Transfusion, KYAMC, Enayetpur, Sirajgonj
  • M Shah Alam Department of Botany, Rajshahi University, Rajshahi

DOI:

https://doi.org/10.3329/kyamcj.v4i2.32279

Keywords:

Argemone mexicana, Antifungal activity, Brine shrimp toxicity

Abstract

The present study determined the antifungal activity of the root of extracts Argemone mexicana against 7 fungi using dichloromethane and methanol as solvent. Among these pathogens, 3 were dermatophytes and the rest 4 were nondermatophytes. The dichloromethane extract of Argemone mexicana exhibited moderate to good activity at concentration of 200 ?g/disc but at concentration of 50 ?g/disc, the same extract showed no activity against the tested fungi. The methanol extract were also inactive against the tested pathogens. In brine shrimp toxicity test, it was observed that LC50 value of the dichloromethane extract of Argemone mexicana was 22.35 ?g/ml. From these findings it is indicative that dichloromethane extract of Argemone mexicana is biologically active and may have antifungal principles that could be useful in fungal diseases.

KYAMC Journal Vol. 4, No.-2, Jan 2014, Page 402-405

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Author Biography

Ainun Nahar, Lecturer, Department of Pharmacology, Rajshahi Medical College, Rajshahi



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Published

2017-04-23

How to Cite

Nahar, A., Habib, A., Awal, M., Rahman, A. S., Mondal, M. G., & Alam, M. S. (2017). Studies on Antifungal Activity and Brine Shrimp Toxicity Argemone mexicana. KYAMC Journal, 4(2), 402–405. https://doi.org/10.3329/kyamcj.v4i2.32279

Issue

Vol. 4 No. 2 (2014)

Section

Original Articles