Antithyroid antibody (TPO-Ab) Status in Type 2 Diabetic Patients

Authors

  • Kamrunnahar Alo Associate Professor, Department of Physiology, Khwaja Yunus Ali Medical College, Sirajganj, Bangladesh
  • Safayet Ahammed Assistant Professor, Department of Respiratory Medicine, Khwaja Yunus Ali Medical College and Hospital, Sirajganj, Bangladesh
  • Mahboba Rahman Assistant Professor, Department of Physiology, University Dental College, Dhaka, Bangladesh
  • Shyamal Chandra Banik Assistant Professor, Department of Physiology, Dhaka National Medical College, Dhaka, Bangladesh
  • Kazi Shihab Uddin Associate Professor and HOD, Department of Medicine, Khwaja Yunus Ali Medical College & Hospital, Enayetpur, Sirajgonj, Bangladesh

DOI:

https://doi.org/10.3329/kyamcj.v14i01.64891

Keywords:

TPO-Ab, Type 2 diabetes mellitus

Abstract

Background: Presence of thyroid peroxidase antibody (TPO-Ab) in type 2 diabetic patients is a risk factor for future development of thyroid dysfunction.
Objective: To observe thyroid antibody status in type 2 diabetic patients.
Materials & Methods: This cross sectional study was carried out in the Department of Physiology, Sir Salimullah Medical College, Dhaka from July 2016 to June 2017. Total 60 subjects including  male and female, age ranged from 40 to 60 years were included in this study, among them 30 were non-diabetic subjects and 30 were type 2 diabetic patients.
Results: In this study, mean serum TPO-Ab level was significantly (<0.01) higher in diabetic subjects in comparison to that of apparently healthy non-diabetic subjects and  mean serum TPO-Ab level was higher in uncontrolled diabetic subjects in comparison to that of controlled diabetic subjects but the difference is not statistically significant. However, On the other hand, among the diabetic patients 6.67% had positive TPO-Ab whereas, among the uncontrolled diabetic patients 11.76% had positive TPO-Ab. There was no correlation between TPO-Ab and HbA1c.
Conclusion: The present study reveals that TPO-Ab may present in type 2 diabetic patients.

KYAMC Journal Vol. 14, No. 01, April 2023: 35-38

 

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Published

2023-07-16

How to Cite

Alo, K., Safayet Ahammed, Mahboba Rahman, Shyamal Chandra Banik, & Kazi Shihab Uddin. (2023). Antithyroid antibody (TPO-Ab) Status in Type 2 Diabetic Patients . KYAMC Journal, 14(01), 35–38. https://doi.org/10.3329/kyamcj.v14i01.64891

Issue

Vol. 14 No. 01 (2023)

Section

Original Articles

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Copyright (c) 2023 KYAMC Journal

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