A2B with Clinically Significant Anti-A1 : A Case Report on the Incidental Finding

Authors

  • Umme Mezbah Akter Specialist, Transfusion Medicine, Evercare Hospital Chattogram
  • Abu Jafar Mohammed Saleh Senior Consultant & Coordinator, Hematology and Stem Cell Transplant, Evercare Hospital Dhaka

DOI:

https://doi.org/10.3329/pulse.v17i2.90029

Keywords:

ABO blood group, Rh typing, Agglutination reaction

Abstract

The purpose of this article is to report an incidental finding of a clinically significant anti-A1 antibody while detecting blood group of an elderly patient. As this antibody is reactive at 37oC, this may cause destruction of transfused A1 red cells and this is the cause of clinical significance. Usually anti-A1 antibodies in plasma are naturally occurring antibodies, not clinically significant because they react best below room temperature, not at body temperature sometimes causing discrepancy during routine blood grouping and crossmatching. For this particular case, some precautions should be taken before blood transfusion to avoid hemolysis.

Pulse Volume 17, Issue 2 2025; 38-40

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Published

2026-05-19

How to Cite

Akter, U. M., & Saleh, A. J. M. (2026). A2B with Clinically Significant Anti-A1 : A Case Report on the Incidental Finding. Pulse, 17(2), 38–40. https://doi.org/10.3329/pulse.v17i2.90029

Issue

Vol. 17 No. 2 (2025)

Section

Case Reports

License

No part of the materials published in this journal may be reproduced, stored or transmitted without prior written permission of the editorial board.