Pathogenesis and Factors associated with Insulin Resistance

Authors

  • Md Atiqur Rahman Associate Professor, Dept. of Community Medicine, AKMMC, Dhaka
  • Tabassum Tahmin Sajani Assistant Professor, Dept. of Community Medicine, AKMMC, Dhaka
  • Kamrunnahar Alo ICU Medical Officer, Khwaja Yunus Ali Medical College & Hospital, Enayetpur, Sirajgonj

DOI:

https://doi.org/10.3329/kyamcj.v5i2.32368

Keywords:

Insulin receptor, Insulin resistance, Dyslipidemia

Abstract

Insulin resistance has been the subject of much debate over the last two decades. Its pathophysiological basis, however, still remains to be clearly understood. Both genetic and environmental factors have been implicated in its pathogenesis. Mutation of genes encoding signal transduction molecules of insulin and acquired factors like aging, diets, physical activity, obesity and related molecular changes, dyslipidemia, hypertension and smoking were proposed by many groups. This review examined both acquired and genetic factors and discussed model of hormone-receptor-postreceptor interactions to explore the molecular basis of insulin resistance.

KYAMC Journal Vol. 5, No.-2, Jan 2015, Page 527-532

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Author Biography

Md Atiqur Rahman, Associate Professor, Dept. of Community Medicine, AKMMC, Dhaka



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Published

2017-04-27

How to Cite

Rahman, M. A., Sajani, T. T., & Alo, K. (2017). Pathogenesis and Factors associated with Insulin Resistance. KYAMC Journal, 5(2), 527–532. https://doi.org/10.3329/kyamcj.v5i2.32368

Issue

Vol. 5 No. 2 (2015)

Section

Review Articles