Incidence of anti-HBc antibody (IgG and IgM) among HBsAg negative apparently healthy blood donors

Authors

  • Nittyananda Shil Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Jolly Biswas Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Ayesha Khatun Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Atiar Rahman Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Nahid Sultana Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Fatema Easmin Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Sonia Sormin Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka

DOI:

https://doi.org/10.3329/bsmmuj.v9i4.30241

Keywords:

Anti-HBc antibody, Blood donor, HBsAg, IgG, IgM

Abstract

In person who is unable to produce HBsAg, anti-HBc antibody is a helpful marker of hepatitis B virus (HBV) infection. In the present study, we have tried to find out the incidence of anti-HBc (IgG and IgM) among blood donors HBsAg negative. People came for donating blood voluntarily or for their relatives (n = 1000) was selected on inclusion and exclusion criteria. Purposefully selected and collated samples were first tested by HBsAg ELISA of third generation reagent. HBsAg negative sample was tested with anti-HBc ELISA. Positive found in the first test was retested. Out of 1,000 samples on duplicate test, 117 positives were detected. The incidence of anti-HBc antibody among apparently healthy blood donors was found 11.7%.

Downloads

Download data is not yet available.
Abstract
719
Download
2776 Read
1295

Author Biography

Nittyananda Shil, Department of Transfusion Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka

 

 

Published

2016-12-05

How to Cite

Shil, N., Biswas, J., Khatun, A., Rahman, A., Sultana, N., Easmin, F., & Sormin, S. (2016). Incidence of anti-HBc antibody (IgG and IgM) among HBsAg negative apparently healthy blood donors. Bangabandhu Sheikh Mujib Medical University Journal, 9(4), 201–204. https://doi.org/10.3329/bsmmuj.v9i4.30241

Issue

Section

Original Articles