Current issues with antibody-conjugated lipid nanoparticles

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DOI:

https://doi.org/10.3329/bsmmuj.v18i1.77310

Keywords:

antibody-conjugated lipid nanoparticles, nonviral gene delivery, immunogenicity

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References

Paunovska K, Loughrey D, Dahlman JE. Drug delivery systems for RNA therapeutics. Nat Rev Genet. 2022 May;23(5):265-280. doi: https://doi.org/10.1038/s41576-021-00439-4

Gao X, Tao Y, Lamas V, Huang M, Yeh WH, Pan B, Hu YJ, Hu JH, Thompson DB, Shu Y, Li Y, Wang H, Yang S, Xu Q, Polley DB, Liberman MC, Kong WJ, Holt JR, Chen ZY, Liu DR. Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents. Nature. 2018 Jan 11;553(7687):217-221. doi: https://doi.org/10.1038/nature25164

Kedmi R, Veiga N, Ramishetti S, Goldsmith M, Rosenblum D, Dammes N, Hazan-Halevy I, Nahary L, Leviatan-Ben-Arye S, Harlev M, Behlke M, Benhar I, Lieberman J, Peer D. A modular platform for targeted RNAi therapeutics. Nat Nanotechnol. 2018 Mar;13(3):214-219. doi: https://doi.org/10.1038/s41565-017-0043-5

Veiga N, Goldsmith M, Granot Y, Rosenblum D, Dammes N, Kedmi R, Ramishetti S, Peer D. Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes. Nat Commun. 2018 Oct 29;9(1):4493. doi: https://doi.org/10.1038/s41467-018-06936-1

Nelson AL. Antibody fragments: hope and hype. MAbs. 2010 Jan-Feb;2(1):77-83. doi: https://doi.org/10.4161/mabs.2.1.10786

Quagliarini E, Renzi S, Digiacomo L, Giulimondi F, Sartori B, Amenitsch H, Tassinari V, Masuelli L, Bei R, Cui L, Wang J, Amici A, Marchini C, Pozzi D, Caracciolo G. Microfluidic Formulation of DNA-Loaded Multicomponent Lipid Nanoparticles for Gene Delivery. Pharmaceutics. 2021 Aug 19;13(8):1292. doi: https://doi.org/10.3390/pharmaceutics13081292

Kirpotin DB, Drummond DC, Shao Y, Shalaby MR, Hong K, Nielsen UB, Marks JD, Benz CC, Park JW. Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models. Cancer Res. 2006 Jul 1;66(13):6732-6740. doi: https://doi.org/10.1158/0008-5472.CAN-05-4199.

Published

2025-02-10

How to Cite

Aayush. (2025). Current issues with antibody-conjugated lipid nanoparticles. Bangabandhu Sheikh Mujib Medical University Journal, 18(1), e77310. https://doi.org/10.3329/bsmmuj.v18i1.77310

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