Debulking surgery for bilateral deforming forefoot tophaceous gout: A case report
Keywords:
gout, gouty tophi, foot deformitiesAbstract
Background: Chronic tophaceous gout develops after prolonged uncontrolled hyperuricaemia and can cause erosive joint damage, progressive deformity, skin thinning, pain and impaired mobility. Surgery may be considered when large tophi cause skin and footwear intolerance or substantial functional disability.
Case description and management: A 45-year-old obese man who worked as a farmer (body mass index, 31.1 kg/m²) presented with a 13-year history of painful bilateral forefoot swelling and progressive deformity, resulting in severe limitations in walking and footwear use. Examination showed bilateral first metatarsophalangeal deformity with lateral deviation of the great toes, large firm periarticular masses, thinned shiny skin, tenderness and markedly restricted motion. Serum urate was 15 mg/dL (laboratory reference range: 3.5–7.2 mg/dL for males) and serum creatinine was 1.6 mg/dL (laboratory reference range: 0.6–1.2 mg/dL for males). Radiographs demonstrated bilateral periarticular tophi with punched-out erosions and overhanging edges. He underwent single-stage bilateral surgical debulking without arthrodesis or reconstruction. Subsequent histopathological examination confirmed gout and excluded malignancy. Mild postoperative wound discharge resolved with local wound care and staged suture removal. At short-term follow-up, both wounds had healed and pain and footwear tolerance had improved modestly; however, residual tenderness, restricted joint motion, tophaceous prominence and hyperuricaemia persisted.
Conclusion: Surgical debulking may relieve local symptoms and reduce skin tension in advanced bilateral forefoot tophaceous gout, but sustained specialist-directed urate-lowering therapy and postoperative surveillance remain essential.
0
0 PDF
0 Review report
0
References
GBD 2021 Gout Collaborators. Global, regional, and national burden of gout, 1990–2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021. Lancet Rheumatol. 2024;6(8):e507–e517. doi: https://doi.org/10.1016/S2665-9913(24)00117-6
FitzGerald JD, Dalbeth N, Mikuls T, Brignardello-Petersen R, Guyatt G, Abeles AM, Gelber AC, Harrold LR, Khanna D, King C, Levy G, Libbey C, Mount D, Pillinger MH, Rosenthal A, Singh JA, Sims JE, Smith BJ, Wenger NS, Bae SS, Danve A, Khanna PP, Kim SC, Lenert A, Poon S, Qasim A, Sehra ST, Sharma TSK, Toprover M, Turgunbaev M, Zeng L, Zhang MA, Turner AS, Neogi T. 2020 American College of Rheumatology guideline for the management of gout. Arthritis Care Res (Hoboken). 2020;72(6):744–760. doi: https://doi.org/10.1002/acr.24180
Poratt D, Rome K. Surgical management of gout in the foot and ankle: a systematic review. J Am Podiatr Med Assoc. 2016;106(3):182–188. doi: https://doi.org/10.7547/14-128
Kasper IR, Juriga MD, Giurini JM, Shmerling RH. Treatment of tophaceous gout: when medication is not enough. Semin Arthritis Rheum. 2016;45(6):669–674. doi: https://doi.org/10.1016/j.semarthrit.2016.01.005
Shiozaki T, Kimura T, Saito M, Kubota M. Three cases of gouty tophus in the foot treated by resection. Cureus. 2023;15(4):e37144. doi: https://doi.org/10.7759/cureus.37144
Aithala PJ, Shetty DK. Gouty arthritis with massive tophaceous deposits involving bilateral metatarsophalangeal joints, surgical treatment with excision and reconstruction: a case report. J Orthop Case Rep. 2025;15(4):69–73. doi: https://doi.org/10.13107/jocr.2025.v15.i04.5448
Xiao W, Ming X, Huang Y, Li J, Jiao Q, Yang J, Zheng L, Zeng Y, Wang R, Cheng S, Bian Y, Yao J. A retrospective analysis of the surgical efficacy for tophi wounds in Hainan province. Front Surg. 2026;13:1752070. doi: https://doi.org/10.3389/fsurg.2026.1752070
Żyluk A, Fliciński F. Outcomes of surgery for gouty tophi in the extremities. Pol Przegl Chir. 2022;94(5):18–22. doi: https://doi.org/10.5604/01.3001.0015.7570
Xie RZ, Li XS, Wu WR, Zhao WQ, Liang YF, Huang JF, Su YX. Postoperative complications and outcomes after surgical treatment for tophaceous gout: a systematic review and meta-analysis. Semin Arthritis Rheum. 2026;80:153038. doi: https://doi.org/10.1016/j.semarthrit.2026.153038
Li Z, Jin M, Wakely PE Jr. Aspiration cytopathology of tophaceous gout: a report of 22 patients. J Am Soc Cytopathol. 2018;7(3):149–153. doi: https://doi.org/10.1016/j.jasc.2018.01.001
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Md Sulaiman

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.