Association between Helicobacter pylori infection and primary open-angle glaucoma

Authors

  • Sayaka Sultana Department of Ophthalmology, Faculty of Surgery, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh
  • Nazneen Khan Department of Ophthalmology, Faculty of Surgery, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh
  • Chonchol Kumar Ghosh Department of Gastroenterology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh
  • Ahmed Abu Saleh Department of Microbiology and Immunology, Faculty of Basic Science and Paraclinical Science, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh
  • Md. Shafiqul Islam Department of Ophthalmology, Faculty of Surgery, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/bsmmuj.v12i1.40484

Keywords:

Helicobacter pylori, Open angle glaucoma, Urea breath test

Abstract

The pathological processes of primary open-angle glaucoma is unknown. Several studies show the relation between Helicobacter pylori infection and primary open-angle glaucoma. The purpose of this study was to assess the association between H. pylori infection and primary open-angle glaucoma. Forty patients of diagnosed primary open-angle glaucoma were selected as case and 40 participants without primary open-angle glaucoma were selected as control as per inclusion and exclusion criteria. Complete clinical evaluation including history, physical examination, relevant ocular examinations and laboratory investigations were performed. Serologic evidence of H. pylori infection was found in 75% of patients with primary open-angle glaucoma and 30% of patients without primary open-angle glaucoma which achieved statistically significant difference (p=0.000, OR=7.00 and CI 95% =2.61-18.74). 13C urea breath test was positive in 70% in case group and 37.5% in control group which also achieved statistically significant difference  (p=0.003, OR=3.89 and CI 95% =1.53-9.87). The findings revealed significant association between H. pylori infection and primary open-angle glaucoma.

 

Downloads

Download data is not yet available.
Abstract
472
Download
357 Read
167

Author Biographies

Sayaka Sultana, Department of Ophthalmology, Faculty of Surgery, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh

 

 

Ahmed Abu Saleh, Department of Microbiology and Immunology, Faculty of Basic Science and Paraclinical Science, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh

Professor

Md. Shafiqul Islam, Department of Ophthalmology, Faculty of Surgery, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh

Professor

Published

2019-03-14

How to Cite

Sultana, S., Khan, N., Ghosh, C. K., Saleh, A. A., & Islam, M. S. (2019). Association between Helicobacter pylori infection and primary open-angle glaucoma. Bangabandhu Sheikh Mujib Medical University Journal, 12(1), 25–28. https://doi.org/10.3329/bsmmuj.v12i1.40484

Issue

Section

Original Articles