SARC-F with anthropometric add-ons for better sarcopenia detection among elderly outpatients visiting a tertiary care hospital: A cross-sectional study

Authors

  • Dermica Ezhil Department of Physiotherapy, Sri Ramachandra Institute of Higher Education and Research, Chennai, India https://orcid.org/0009-0006-2070-6483
  • Agnes Kaviya Department of Physiotherapy, Sri Ramachandra Institute of Higher Education and Research, Chennai, India
  • Chrysolyte Mohanan Department of Physiotherapy, Sri Ramachandra Institute of Higher Education and Research, Chennai, India https://orcid.org/0000-0002-7058-7447
  • Antony Leo Aseer Department of Physiotherapy, Sri Ramachandra Institute of Higher Education and Research, Chennai, India
  • Subbiah Kanthanathan Department of Physiotherapy, Sri Ramachandra Institute of Higher Education and Research, Chennai, India
  • Soundararajan Kannan Department of Physiotherapy, Sri Ramachandra Institute of Higher Education and Research, Chennai, India

Keywords:

sarcopenia, SARC- F, calf girth, arm circumference, AWGS

Abstract

Background: Early identification of sarcopenia, a progressive skeletal muscle disorder, remains challenging. Although the Strength, Assistance with walking, Rise from a chair, Climb stairs, and Falls (SARC-F) questionnaire is widely recommended for sarcopenia screening, its limited sensitivity reduces its effectiveness in clinical practice. To improve diagnostic performance, modified versions incorporating anthropometric measurements, calf girth (CalF) and including arm circumference (AC), have been developed and validated in different ethnic populations. This study aimed to evaluate the diagnostic accuracy of the SARC-CalF+AC questionnaire among older adults in Indian population.

Methods: This cross-sectional study included 360 older adults attending the outpatient department of a tertiary care hospital. Participants with preserved cognitive function and independent walking ability were enrolled. The diagnostic performance of the SARC-F and SARC-CalF+AC screening tools was evaluated against the Asian Working Group for Sarcopenia (AWGS) diagnostic criteria.

Results: Approximately one in six were women; Participants mean age was 64 years. Among them 131 were diagnosed with sarcopenia, yielding a prevalence of 36.4% (95% Confidence Interval, 31.6–41.5). The SARC-F questionnaire demonstrated a sensitivity of 22.9% and a specificity of 80.9%. In comparison, the SARC-CalF+AC questionnaire achieved substantially higher sensitivity (75.6%) and specificity (88.2%).

Conclusion: The addition of calf girth and arm circumference measurements significantly improved the diagnostic performance of the SARC-F questionnaire, making SARC-CalF+AC a more effective screening tool for sarcopenia in older adults. 

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References

Tagliafico AS, Bignotti B, Torri L, Rossi F. Sarcopenia: how to measure, when and why. Radiol Med. 2022;127(3):228-237. doi: https://doi.org/10.1007/s11547-022-01450-3

Endo K, Sato T, Kakisaka K, Takikawa Y. Calf and arm circumference as simple markers for screening sarcopenia in patients with chronic liver disease. Hepatol Res. 2021;51(2):176-189. doi: https://doi.org/10.1111/hepr.13589

Krzymińska-Siemaszko R, Deskur-Śmielecka E, Kaluźniak-Szymanowska A, Murawiak M, Wieczorowska-Tobis K. Comparison of diagnostic value of the SARC-F and its four modified versions in Polish community-dwelling older adults. Clin Interv Aging. 2023;18:783-797. doi: https://doi.org/10.2147/CIA.S408616

Hu FJ, Liu H, Liu XL, Jia SL, Hou LS, Xia X, Dong BR. Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia. Clin Interv Aging. 2021 Jun 15;16:1095-1104. doi: https://doi.org/10.2147/CIA.S311081

Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, et al. Asian Working Group for Sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment. J Am Med Dir Assoc. 2020;21(3):300-307.e2. doi: https://doi.org/10.1016/j.jamda.2019.12.012

Zhou J, Li T, Chen X, Wang M, Jiang W, Jia H. Comparison of the diagnostic value of SARC-F and its three modified versions for screening sarcopenia in Chinese community-dwelling older adults. J Nutr Health Aging. 2022;26(1):77-83. doi: https://doi.org/10.1007/s12603-021-1718-z

Kalra S, Shaikh IA, Shende S, Kapoor N, Unnikrishnan AG, Sharma OP, et al. An Indian consensus on sarcopenia: epidemiology, etiology, clinical impact, screening, and therapeutic approaches. Int J Gen Med. 2025;18:1731-1745. doi: https://doi.org/10.2147/IJGM.S510412

Pal R, Aggarwal A, Singh T, Sharma S, Khandelwal N, Garg A, Bhansali A, Kumar A, Yadav U, Singh P, Dhiman V, Dutta P, Bhadada SK. Diagnostic cut-offs, prevalence, and biochemical predictors of sarcopenia in healthy Indian adults: The Sarcopenia-Chandigarh Urban Bone Epidemiological Study (Sarco-CUBES). Eur Geriatr Med. 2020 Oct;11(5):725-736. doi: https://doi.org/10.1007/s41999-020-00332-z

Lee RC, Wang Z, Heo M, Ross R, Janssen I, Heymsfield SB. Total-body skeletal muscle mass: development and cross-validation of anthropometric prediction models. Am J Clin Nutr. 2000;72(3):796-803. doi: https://doi.org/10.1093/ajcn/72.3.796

Barbosa-Silva TG, Menezes AM, Bielemann RM, Malmstrom TK, Gonzalez MC, Grupo de Estudos em Composição Corporal e Nutrição (COCONUT). Enhancing SARC-F: improving sarcopenia screening in the clinical practice. J Am Med Dir Assoc. 2016;17(12):1136-1141. doi: https://doi.org/10.1016/j.jamda.2016.08.004

Nguyen TN, Nguyen AT, Khuong LQ, Nguyen TX, Nguyen HTT, Nguyen TTH, Hoang MV, Pham T, Nguyen TN, Vu HTT. Reliability and Validity of SARC-F Questionnaire to Assess Sarcopenia Among Vietnamese Geriatric Patients. Clin Interv Aging. 2020 Jun 9;15:879-886. doi: https://doi.org/10.2147/CIA.S254397

Woo J, Leung J, Morley JE. Validating the SARC-F: a suitable community screening tool for sarcopenia? J Am Med Dir Assoc. 2014;15(9):630-634. doi: https://doi.org/10.1016/j.jamda.2014.04.021

Krzymińska-Siemaszko R, Deskur-Śmielecka E, Kaluźniak-Szymanowska A, Lewandowicz M, Wieczorowska-Tobis K. Comparison of diagnostic performance of SARC-F and its two modified versions (SARC-CalF and SARC-F+EBM) in community-dwelling older adults from Poland. Clin Interv Aging. 2020;15:583-594. doi: https://doi.org/10.2147/CIA.S250508

Jeng C, Zhao LJ, Wu K, Zhou Y, Chen T, Deng HW. Race and socioeconomic effect on sarcopenia and sarcopenic obesity in the Louisiana Osteoporosis Study (LOS). JCSM Clin Rep. 2018 Jul-Dec;3(2):e00027. PMID: 31463425

Published

25-07-2026

How to Cite

Ezhil , D., Kaviya, A., Mohanan, C., Aseer, A. L., Kanthanathan, S., & Kannan, S. (2026). SARC-F with anthropometric add-ons for better sarcopenia detection among elderly outpatients visiting a tertiary care hospital: A cross-sectional study. Bangabandhu Sheikh Mujib Medical University Journal, 19(3), e82900. https://doi.org/10.3329/bsmmuj.v19i3.82900

Issue

Section

Research Article

How to Cite

Ezhil , D., Kaviya, A., Mohanan, C., Aseer, A. L., Kanthanathan, S., & Kannan, S. (2026). SARC-F with anthropometric add-ons for better sarcopenia detection among elderly outpatients visiting a tertiary care hospital: A cross-sectional study. Bangabandhu Sheikh Mujib Medical University Journal, 19(3), e82900. https://doi.org/10.3329/bsmmuj.v19i3.82900