Obesity phenotypes and their adipocyte dysfunction among the attendants at outpatient department

Authors

  • Sabikun Naher Department of Biochemistry and Molecular Biology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka http://orcid.org/0000-0001-5941-1742
  • M. Mozammel Hoque Department of Biochemistry and Molecular Biology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Hasan Imam Department of Internal Medicine, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka

DOI:

https://doi.org/10.3329/bsmmuj.v11i2.36507

Keywords:

Adipocyte dysfunction, Healthy obese, Metabolically obese Normal weight, Overweight, Phenotype, Unhealthy obese

Abstract

The present study was aimed to find out the frequency of obesity phenotypes and to correlate adipocyte dysfunction with different obesity phenotypes. A total of 1,507 apparently healthy adults attending the outpatient department were grouped into three based on body mass index which were then further categorized into six groups according to metabolically unhealthy or healthy phenotypes by the presence or absence of metabolic syndrome. Of them, metabolically obese normal weight, overweight, healthy obese and unhealthy obese groups were included as obesity phenotypes. Then by purposive sampling, leptin and adiponectin concentration of 184 subjects with different phenotypes were measured to find out the adipocyte dysfunction. Metabolically obese overweight followed by metabolically unhealthy obese were more prevalent i,e.,  24.9% and 19.5%. All obesity phenotypes except metabolically obese normal weight were significantly documented with adipocyte dysfunction (p<0.05).

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Published

2018-05-27

How to Cite

Naher, S., Hoque, M. M., & Imam, H. (2018). Obesity phenotypes and their adipocyte dysfunction among the attendants at outpatient department. Bangabandhu Sheikh Mujib Medical University Journal, 11(2), 112–117. https://doi.org/10.3329/bsmmuj.v11i2.36507

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Section

Original Articles