Association of vitamin D and insulin resistance among the adults with newly detected prediabetes attending in a tertiary care hospital of Bangladesh

Authors

  • Murshed Ahamed Khan Department of Endocrinology & Metabo- lism, BSMMU, Dhaka, Bangladesh
  • Md Fariduddin Department of Endocrinology & Metabo- lism, BSMMU, Dhaka, Bangladesh
  • Shahjada Selim Department of Endocrinology & Metabo- lism, BSMMU, Dhaka, Bangladesh
  • Mohammad Masum Alam Department of Biochemistry, BSMMU, Dhaka, Bangladesh
  • Md Shahed Morshed Kurmitola General Hospital, Dhaka, Bangladesh
  • Md Habibul Ghani Jinjira 20 beded hospital, Keranigonj, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/bsmmuj.v14i4.56617

Keywords:

Vitamin D, Prediabetes, Insulin resistance

Abstract

Several studies have found an inverse association between vitamin D level and insulin resistance (IR) causing prediabetes and diabetes. So the current study was done to find out the association between serum vitamin D level and IR among adults with prediabetes. This cross-sectional study was carried out in 140 newly detected adults with prediabetes according to ADA 2018 criteria. The 25(OH) D cutoffs to define deficiency and insufficiency were used according to Endocrine Society (USA) criteria, measurement of vitamin D & insulin (fasting) was done by chemiluminescent microparticle immunoassay (CMIA). Data were analyzed using SPSS (version 22.0) and presented as table and figure. P-value ≤0.05 was considered significant. In this study, most of the population was 30 years and above (73%). The Male-female ratio was 1:7, the majority of participants came from urban areas (81%) and it was observed that there was an increasing trend of insulin resistance across increasing severity of vitamin D deficiency though it was not statistically significant (p= 0.74). In conclusion, vitamin-D deficiency/insuffi- ciency is common among individuals with prediabetes in our country, but there were no associ- ation had been found between vitamin D and insulin resistance in individuals with prediabetes

BSMMU J 2021; 14(4): 157-162

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Published

2022-03-14

How to Cite

Khan, M. A. ., Fariduddin, M. ., Selim, S. ., Alam, M. M. ., Morshed, M. S. ., & Ghani, M. H. . (2022). Association of vitamin D and insulin resistance among the adults with newly detected prediabetes attending in a tertiary care hospital of Bangladesh. Bangabandhu Sheikh Mujib Medical University Journal, 14(4), 157–162. https://doi.org/10.3329/bsmmuj.v14i4.56617

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Original Articles