Comparison of serum homocysteine level in young and middle-aged adult patients with coronary artery disease
Homocysteine in coronary artery disease
DOI:
https://doi.org/10.3329/bsmmuj.v15i3.63156Keywords:
Serum homocysteine, Coronary artery disease, Young adultsAbstract
Deaths due to coronary artery disease have been increasing in young people aged <40. Studies have reported an association between these deaths with hyperhomocysteinemia. The aim of this study was to compare serum homocysteine levels in middle-aged patients with coronary artery disease. This cross-sectional study was conducted among 52 cardiology inpatients of Bangabandhu Sheikh Mujib Medical University, Dhaka, from March 2021 to February 2022. Among them, 26 were young adults (<40 years, Group I), and 26 were middle-aged (≥40 years, Group II). Serum homocysteine was measured in all of them using an automated immunoassay analyzer. The younger patients had higher (P=0.001) median homocysteine (interquartile range) level, 13.5 (7.7 –28.4 mmol/L) compared to the middle-aged group, 10.0 (5.9 – 38.5 mmol/L). The hyperhomocysteinemia (>15 mmol/L) was 16.2% in Group I compared to 12.4% in Group II (P=0.001). Therefore, control measures for keeping homocysteine levels within the normal range in young people might be useful.
BSMMU J 2022; 15(3): 197-200
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Copyright (c) 2022 Rokshana Begum, Mohammad Monzurul Alam Bhuiyan, Sheuly Ferdousi, Mst Shaila Yesmin, Debatosh Paul, Tuhin Sultana, Md Quddusur Rahman, Md Saiful Islam, Khandoker Abdur Rahim, Mohammad Fakhrul Islam Khaled
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