Dose- and time-related platelet response with apheresis platelet concentrates and pooled platelets

Abstract

This study was carried out to compare the post-transfusion platelet increment between the apheresis platelet concentrate (n=74) and pooled platelets (n=54). Pre- and post-transfusion platelet count of the recipient were carried out by automated hematology analyzer. In apheresis platelet concentrate group, the mean 24 hours post-transfusion platelet increment was 47 x 10⁹/L which was statistically significant (p<0.001). On the other hand, in pooled platelets group, the mean 24 hours posttransfusions platelet count increment was 11.0 x 10⁹/L which was also statistically significant (p<0.001). This study concluded that the transfusion of apheresis platelet concentrate was more useful than the transfusion of pooled platelets in terms of platelet count increment and requirement of donor.